purpose: to evaluate and compare tear secretion and tear film instability following laser in situ keratomileusis (lasik) and laser assisted subepithelial keratectomy (lasek). methods: in a randomized clinical trial, 30 eyes of 15 patients underwent lasik and 30 eyes of 15 patients underwent lasek to correct myopia. tear secretion and tear film instability were tested preoperatively, 2 and 6 wee...

PURPOSE To evaluate epithelial healing and visual outcome after laser-assisted subepithelial keratectomy (LASEK) without alcohol de-epithelialization and to compare this technique to photorefractive keratectomy (PRK) in myopia. METHODS In a series of 1953 patients undergoing bilateral myopic PRK, an epithelial flap could be obtained by manual de-epithelialization in the left eye of 56 patient...

PURPOSE To evaluate epithelial healing, postoperative pain, and visual and refractive outcomes after photorefractive keratectomy (PRK) using three epithelial removal techniques. DESIGN Prospective, nonrandomized, comparative trial. METHODS SETTING Department of Ophthalmology, Yonsei University College of Medicine and Balgensesang Ophthalmology Clinic, Seoul, Korea. INTERVENTIONS For th...

PURPOSE To compare changes in corneal nerve fibers and keratocyte density by confocal microscopy after laser-assisted in situ keratomileusis (LASIK) and laser epithelial keratomileusis (LASEK). DESIGN Prospective, nonrandomized comparative clinical trial. METHODS Fifty-six eyes of 28 patients who underwent LASIK and 52 eyes of 26 patients who underwent LASEK were included. Confocal microsco...

PURPOSE To compare corneal reepithelialization, pain scores, ocular discomfort, and tear production after photorefractive keratectomy (PRK) and butterfly laser epithelial keratomileusis (LASEK). METHODS This prospective, randomized, double-masked study comprised 102 eyes of 51 patients who underwent laser refractive surgery. Each patient was randomized to have one eye operated on with PRK and...

BACKGROUND To compare the corneal high-order aberrations (HOAs), asphericity and regularity after Q-value guided laser in situ keratomileusis (LASIK) and laser epithelial keratomileusis (LASEK) in high myopic astigmatism. METHODS In this retrospectively comparative study, we measured the corneal HOAs, asphericity indices (Q values) and corneal regularity indices preoperatively and 36 months p...

PURPOSE To evaluate the visual and refractive outcome for four wavefront-guided surface ablation (WGSA) techniques (LASEK, LASEK flap-off [LASEK FO], Epi-LASIK, and Epi-LASIK flap-off [Epi-LASIK FO]) in a large myopic population. METHODS This retrospective review included 1000 myopic eyes (spherical equivalent [SE] -1.0 to -8.0 diopters [D]) treated with WGSA (VISX STAR S4 with IR) using four...

The axonal transport of the diverse group of polypeptides characteristic of slow component b (SCb), or Group IV, may be accomplished either by a bulk flow mechanism acting on each of the individual polypeptides or by their movement through the axoplasm as part of a physical complex or structural assembly. In order to determine if the SCb polypeptides travel as a cohesive unit (which would be co...

purpose : to compare the visual and refractive outcomes of laser in situ keratomileusis (lasik) versus laser assisted subepithelial keratectomy (lasek) in the treatment of low to moderate myopia and astigmatism methods : a retrospective comparative case series study comprised 2,474 eyes of patients with manifest refraction spherical component lower than -5.00 diopters (d) and cylinder component...