Dichboroablyblawsone [2-hydroxy-3-(3,3-dichboroallyb)-1 ,4naphthoquinone, NSC 126771 ] is of interest as an antiturnor agent. Like certain other naphthoquinones, it is known to be a respiratory poison as a result of interference with electron transport, but it has not been shown that this action is respon sible for its toxicity or antitiumor activity. Studies in cultured Li 210 cells showed tha...

CONTEXT Lawsonia inermis Linn. (Lythraceae) or henna has been used since the earliest times as a medicine, preservative, and cosmetic. It has long been recommended in traditional medicine as an astringent, purgative, and abortifacient. OBJECTIVE Lawsone and six extracts of L. inermis plant, used by Algerian traditional healers to treat infectious diseases, were screened for their antifungal a...

The fast development of multi-drug resistant (MDR) organisms increasingly threatens global health and well-being. Plant natural products have been known for centuries as alternative medicines that can possess pharmacological characteristics, including antimicrobial activities. The antimicrobial activities of essential oil (Calli oil) extracted from the Calligonum comosum plant by hydro-steam di...

The effect of Lawsonia inermis Linn Leaf extract on electroless deposition Zinc-P alloy mild steel is studied in alkaline solutions. experimental processing parameters the rate investigated during plating. bath compositions and operating conditions are optimized. results obtained show inclusion Zn-P coating found to be increased by increasing volume additives from 0.5ml 1.5ml. Structured UV - A...

OBJECTIVES Lawsone (1,4 naphthoquinone) is a non redox cycling compound that can be catalyzed by DT diaphorase (DTD) into 1,2,4-trihydroxynaphthalene (THN), which can generate reactive oxygen species by auto oxidation. The purpose of this study was to evaluate the toxicity of the phytomarker 1,4 naphthoquinone and its metabolite THN by using the molecular docking program AutoDock 4. METHODS T...

A new and efficient method for the synthesis of hexahydropyrimidine-fused 1,4-naphthoquinones in one step with high yields from the reaction of lawsone with 1,3,5-triazinanes was developed.

Regarding the therapeutic effects and traditional applications of henna, it was tried to isolate and purify Lawsone from the leaves of henna marketed in Ahwaz city of Iran by various methods of maceration and Soxhlet extraction techniques in different polar and non-polar solvents. Maceration of the powdered leaves in hot water with stirring for around 6 hours was carried out followed by additio...

Novel enzymes involved in the biosynthesis of plant secondary metabolites have been discovered in our laboratory from both differentiated plants and in vitro cultures of Thai medicinal plants. The discovered enzymes included (1) geranylgeraniol-18-hydroxylase from Croton sublyratus containing plaunotol, an anti-peptic ulcer diterpenoid, (2) dopamine-secologanin condensing enzymes from Alangium ...

It has been postulated that the development of resistance to known anti-bacterials could be overcome by identifying new drugs. Hence, the objective of the work is to improve upon the existing anti-bacterial activity of the herbal drug molecule. The main purpose is to synthesize and characterize herbo-mineral complexes and evaluate them for antibacterial activity. This research study deals with ...

Lawsone a natural pigment present in the henna leaves has been used as a skin and hair dye since 1400 BC. The concentration of this natural compound in leaves varies from place to place depending upon many of the environmental factors and the highest quantity reported so far is about 1% of the dry mass. Heretofore, it has been reported that natural colored extracts and isolate from Henna leaves...