The rate of degradation of oxidatively modified low density lipoprotein (Ox-LDL) by human endothelial cells was similar to that of unmodified low density lipoprotein (LDL), and was approximately 2-fold greater than the rate of degradation of acetylated LDL (Ac-LDL). While LDL and Ac-LDL both stimulated cholesterol esterification in endothelial cells, Ox-LDL inhibited cholesterol esterification ...

Cholesterol absorption, fecal elimination, and synthesis and low density lipoprotein (LDL) metabolism were measured in 29 middle-aged men while on their normal diet and a diet low in fat and cholesterol, and the obtained values were related to apoprotein (apo) E phenotypes. Basal cholesterol absorption efficiency was positively related to production rate (PR) for LDL apo B and negatively to cho...

The aim of the present study was, first, to investigate whether cholesterol (C) absorption, enhanced by cholesterol feeding, was related to synthesis of cholesterol, serum level of low density lipoprotein (LDL)-C, and receptor activity for LDL apolipoprotein (apo) B in healthy men. Secondly, we were interested in whether apolipoprotein E (apoE) phenotypes contributed to cholesterol and LDL apoB...

Introduction: Low-density lipoprotein cholesterol (LDL-C) levels in serum is the basis of diagnosis, classification and management hypercholesterolemia as per current recommendations Adult Treatment Panel III National Cholesterol Education Program. Friedewalds formula used most laboratories to measure LDL-C indirectly. But, not reliable always. Now-a-days, various homogenous assay kits for dire...

La variabilité intra-individuelle du cholestérol, et plus précisément LDL-cholestérol, mais, possiblement aussi, celle HDL-cholestérol apparaissent comme potentiellement délétères. Plusieurs études ont objectivé une association indépendante entre la d’une part, le risque d’accidents cardiovasculaires (infarctus myocarde, accident vasculaire cérébral) mortalité globale, d’autre part. Par ailleur...

Nauclea latifolia (N. latifolia) and Pteleopsis suberosa (P. suberosa) are two medicinal plants used to treat several pathologies linked oxidative stress. This study aims the effects of ethanolic extracts from those on consequences cholesterolemic overload. Oxidative stress was induced by In vitro antioxidant activity evaluated using DPPH, total phenolic compounds flavonoids assays; while in vi...

Previous studies have suggested that greater arterial concentrations of undegraded low density lipoprotein (LDL) and/or greater arterial rates of LDL degradation may play role(s) in determining regional differences in arterial susceptibility to atherosclerosis in rabbits (Schwenke and Carew, Arteriosclerosis 1989;9:895-918). The White Carneau (WC) pigeon is also useful for investigating potenti...