Donor cell leukaemia (DCL) is a rare complication of allogenic hematopoietic cell transplantation (HCT). We report the case of a female patient with acute promyelocytic leukaemia (APL), FAB type M3, who developed acute myeloid leukaemia (AML) type M5 of donor origin 17 years after allogenic bone marrow transplantation (BMT) from her HLA-matched sister. Morphology and immunophenotyping showed di...

Acute lymphoblastic leukaemia (ALL) accounts for about 78% of all leukaemia diagnosed in children. ALL is the most common cancer in children [2] . Acute myeloid leukaemia (AML) is the next most common and accounts for 15% of childhood leukaemia. The incidence rates are highest in infants (under 1 year old) and show little variation from age 3 years onwards. Chronic myeloid leukaemia (CML) accou...

Leukaemia is a blood cancer disease that contributes to the increment of mortality rate in Malaysia each year. There are two main categories for leukaemia, which are acute and chronic leukaemia. The production and development of acute leukaemia cells occurs rapidly and uncontrollable. Therefore, if the identification of acute leukaemia cells could be done fast and effectively, proper treatment ...

background: leukaemia is a chronic disease with unknown cause whose treatment is included various stages such as bone marrow transplantation. some research accredited the role of quality of life before transplantation in physical well-being after bmt. the purpose of the present research was to study the relation between quality of life dimensions and physical well-being of post-bmt in patients ...

case-control study of leukaemia and lymphoma among young people near Sellafield nuclear plant in West Cumbria. BMJ 1990;300:423-9. 17 Gardner MJ. Paternal occupations of children with leukaemia. BMJ 1992;305: 715. 18 Beral V. Leukaemia and nuclear installations. BMJ 1990;300:41 1-2. 19 McLaughlin JR, Anderson TW, Clarke EA, King W. Occupational exposure of fathers to ionizing radiation and the ...

By using a quantitative RNA-RNA solution hybridisation method, the average number of mdrl RNA transcripts per cell was measured in total nucleic acid extracts of leukaemic cells from patients with acute leukaemia. The results in different types of leukaemia were (number of patients with detectable mdrl RNA/total number of patients; median number of transcripts per cell in samples with detectabl...

background and aims: bovine leukaemia virus (blv) is an oncogenic member of the genus deltaretrovirus of the family retroviridae. blv is the causative agent of enzootic bovine leukaemia and infects cattle worldwide, imposing economic impact on the dairy cattle industry. the purpose of this study was to estimate the seroprevalence of blv in cattle in some provinces of iran. materials and methods...

Leukaemia accounts for around 3% of all cancer types diagnosed in adults, and is the most common type children paediatric age. There increasing interest use mathematical models oncology to draw inferences make predictions, providing a complementary picture experimental biomedical models. In this paper we recapitulate state art modelling leukaemia growth dynamics, time response treatment. We int...

The use of intelligent techniques in medicine has brought a ray of hope in terms of treating leukaemia patients. Personalized treatment uses patient's genetic profile to select a mode of treatment. This process makes use of molecular technology and machine learning, to determine the most suitable approach to treating a leukaemia patient. Until now, no reviews have been published from a computat...

AIMS Because of the observation of an abundance of leukaemia/lymphoma cell microparticles in the bone marrow aspiration sample of a patient with Burkitt's leukaemia at diagnosis, the occurrence of this phenomenon in leukaemia/lymphoma samples with available immune phenotyping data was investigated retrospectively. METHODS Flow cytometric immune phenotyping and spontaneous apoptosis analysis o...