Leukoplakia is one of the most frequently encountered white lesions by the clinicians. The definitions and terminologies associated with leukoplakia have been proposed by various authors. Also, various attempts have been made to clinically and histopathologically grade leukoplakia by evaluating different criteria. Although there are numerous reviews that have discussed the definitions and class...

OBJECTIVE To assess the effectiveness and identify vocal fold leukoplakia types appropriate for nonsurgical treatment. METHODS The vocal fold leukoplakia in 178 patients was divided by gross appearance into three subtypes: flat and smooth, elevated and smooth, and rough. All patients received nonsurgical treatment including smoking and drinking cessation, voice rest, omeprazole, and Chinese m...

Background: Oral Leukoplakia is the most common potentially malignant lesion of the oral mucosa. It is seen most frequently in middle-aged and older men, with an increasing prevalence with age. Less than one percent of men below the age of 30 years have oral leukoplakia. The etiology is multifactorial but the most common cause associated with oral leukoplakia is tobacco consumption. Aim: To est...

BACKGROUND Leukoplakia, is a precancerous lesion that is most commonly encountered in the oral cavity. The grade of dysplasia is presumed to be the most important indicator of malignant potential. There are many promising aspects in advanced methods for the evaluation of oral precancer and cancer. Among these methods, electron microscopic examination predicts the true biologic potential more ac...

OBJECTIVE This study analysed differences in clinicopathological features of oral leukoplakia in different racial groups in the greater Johannesburg area of South Africa, with emphasis on the black population. MATERIAL AND METHODS The retrospective review included cases diagnosed clinically as oral leukoplakia and histologically as hyperkeratosis without dysplasia, hyperkeratosis with mild, m...

Oral leukoplakia is one of the common precancerous lesions in oral mucosa. To compare the biological characteristics and regenerative capacities of mesenchymal stem cells (MSCs) from oral leukoplakia (epithelial hyperplasia and dysplasia) and normal oral mucosa, MSCs were isolated by enzyme digestion. Then these cells were identified by the expression of MSC related markers, STRO-1, CD105 and C...

INTRODUCTION Proliferative verrucous leukoplakia is a multifocal and progressive lesion of the oral mucosa, with unknown etiology, and commonly resistant to all therapy attempts with frequent recurrences. It is characterized by a high rate of oral squamous cell carcinoma and verrucou carcinoma transformations. OBJECTIVE To analyze the studies about Proliferative verrucous leukoplakia and deve...

Leukoplakia is the most common potentially malignant disorder of the oral mucosa. The frequency of dysplastic or malignant change varies from 15.6-39.2% in different studies. The risk of developing malignancy at the lesional site is 5 times greater in patients with leukoplakia than in patients without them. Hence, it is necessary for early diagnosis of both leukoplakia and Oral squamous cell ca...

The word "leukoplakia" literally means a white patch. Over the years, there has been a lot of confusion regarding the usage of this term, as there are numerous specific oral white lesions that must have been referred to as leukoplakia. WHO Collaborative Reference Centre for Oral Precancerous Lesion 1 defined leukoplakia as "A white patch, after clinical and laboratory investigations, cannot be ...

BACKGROUND Human papillomavirus (HPV) and p53 alterations are speculated to play a role in carcinogenesis. This study was carried out to find out the association of HPV and p53 with precancerous lesions of the oral cavity such as leukoplakia: The objective of this study was to find the association among human papilloma virus (HPV) 16 infections and p53 polymorphism in tobacco using the oral leu...