Large hemispheric infarction (LHI), also known as malignant middle cerebral infarction, is a devastating disease associated with significant disability and mortality. Clinicians and family members are often faced with a paucity of high quality clinical data as they attempt to determine the most appropriate course of treatment for patients with LHI, and current stroke guidelines do not provide a...

BACKGROUND Methylation levels of genomic repeats such as long interspersed nucleotide elements (LINE-1) are representative of global methylation status and play an important role in maintenance of genomic stability. The objective of the study was to assess LINE-1 methylation status in colorectal cancer (CRC) in relation to adenomatous and malignant progression, tissue heterogeneity, and TNM-sta...

We evaluated reproductive isolation in two species of palms (Howea) that have evolved sympatrically on Lord Howe Island (LHI, Australia). We estimated the strength of some pre- and post-zygotic mechanisms in maintaining current species boundaries. We found that flowering time displacement between species is consistent across in and ex situ common gardens and is thus partly genetically determine...

BACKGROUND Biologics containing growth factors are frequently used to enhance healing after musculoskeletal injuries. One mechanism of action is thought to be though the ability of biologics to induce homing and migration of endogenous mesenchymal stromal cells (MSCs) to a target tissue. However, the ability of biologics to stimulate chemotaxis (directed migration of cells) and chemokinesis (in...

Penelitian ini bertujuan untuk mengetahui bagaimana asesmen kognitif berbasis HOTS terimplementasikan pada materi PAI kelas IX dengan basis pembelajaran proyek di SMP IT LHI. Tidak semua sekolah menerapkan HOTS, padahal pencapaian peserta didik dalam belajar diukur soal-soal yang mencangkup ranah level 4,5, dan 6. Merupakan penelitian kualitatif mengumpulkan data wawancara dokumentasi. Teknik p...

background: the objective of this study is to optimize the effective dose of heparin and ligustrazine hydrochloride injection (lhi) for drug combination. materials and methods: the animal clinical study of lhi was performed by the rat’s model of induced arteriovenous shunt thrombosis. experimental animals were grouped into several groups and separately treated with both lhi (20, 40, 80 mg/kg, i...

Long range phasing (LRP) is a fast and accurate rule based method which uses information from both related and unrelated individuals by invoking the concepts of surrogate parents and Erdös numbers (Kong et al., 2008). Recursive long range phasing and long haplotype imputation (RLRPLHI; Hickey et al., 2009) is an extended LRP algorithm with increased robustness partially due to the extra long ha...

Understanding the processes underlying the origin of species is a fundamental goal of biology. It is widely accepted that speciation requires an interruption of gene flow between populations: ongoing gene exchange is considered a major hindrance to population divergence and, ultimately, to the evolution of new species. Where a geographic barrier to reproductive isolation is lacking, a biologica...

Mulberry (Morus spp.) is a perennial tree cultivated for its foliage to rear the domesticated silkworm, Bombyx mori L. Mulberry has improved through conventional breeding in general aims to improve the quantity and quality of leaf yield, which have direct bearing on silk productivity. Leaf senescence is one of the major constraints, which restricts the quantity of quality leaf availability for ...

This paper presents a data-driven cluster sampling framework for parsing scene images into generic regions (such as the sky, mountain and water) and objects (such as cows, horses and cars). We adopt generative models for both generic regions and objects, thus their likelihood probabilities are comparable and are learned under a common information projection principle. The inference algorithm fo...