A 65-year-old man had relapsed follicular lymphoma. When he suffered a fifth relapse, he received a regimen containing bendamustine and rituximab (BR). Four weeks later, he presented with systemic erythema, swelling and bullous lesions of lips, the oral cavity, andnasal mucosa and eye pain. He could not open his mouth and had severe pain. Steven–Johnson syndrome/toxic epidermal necrolysis was d...

Dental Update – November 2002 Abstract: Lichen planus is a relatively common, often clinically distinctive, mucocutaneous condition with an uncertain aetiology. One variant of lichen planus is the so-called ‘lichenoid drug eruption’. In contrast to idiopathic lichen planus, lichenoid drug eruptions, where practicable, may be managed by substitution of the offending drug. The dental clinician is...

Lichenoid drug eruptions can mimic idiopathic lichen planus and other dermatoses. The list of drugs that can cause them is long and growing steadily. Although cutaneous side effects of antipsychotics are rare, various cutaneous manifestations have been reported in association with olanzapine. We present the case of a patient who developed an atypical lichenoid eruption due to olanzapine. A revi...

Lichenoid reaction represents a family of oral lesions identical, both clinically and histologically to oral lichen planus. The triggering factor for this lesion varies from medicines to dental materials, usually demonstrating a cause-effect relationship unlike lichen planus. We present a typical case of lichenoid reaction on the buccal mucosa that appeared in response to betel quid which progr...

This off-center fold case depicts the difficult differential diagnosis for benign lichenoid keratosis. It is challenging to diagnosis this benign lesion through clinical exam, dermoscopy, and even dermatopathology. Given its similar appearance to regressed melanoma, it is important to be cognizant of both and up to date on the dermatopathology clues.

Sir, Lichen myxedematosus (LM) is a rare pathology, described for the ® rst time by Dubreuilh (1) in 1906, characterized by the accumulation of mucinous material in the dermis, with no disorder in the thyroid gland, and usually associated with paraproteinemia. In 1953, Montgomery & Underwood (2) classi® ed LM into 4 clinical types: (1) a generalized lichenoid eruption, later denominated sclerom...

Pseudonests or pseudomelanocytic nests represent aggregates of cells and cell fragments, including keratinocytes, macrophages, lymphocytes, and occasional melanocytes. Pseudomelanocytic nests in the setting of lichenoid inflammation can mimic atypical melanocytic proliferations. Several reports documented nonspecific staining of pseudonests with melanoma antigen recognized by T cells-1/Melan-A,...

Oral lichenoid reactions are disease conditions with definite identifiable aetiology. It can occur either due to intake of drug i.e. lichenoid drug eruptions or due to contact with some potential irritants which majority of times are dental materials. Some other allergens including certain food items are also reported. Some systemic conditions such as chronic liver disease, hepatitis C virus in...

Lichenoid reaction is a mucosal lesion characterized by linear whitish striae appearing on the mucosa and is triggered by external factors like restorative materials, betel nut, tobacco, graft versus host reaction and drugs. A detailed history will help in delineating the two lesions. The review provides an insight into the clinical, histological features and the malignant potential of Lichenoi...