Muscle injury has been documented following eccentric exercise bouts in skeletal muscle (Faulkner 1985, Duan et al. 1988, Lieber & Fride!n 1988). Insights into the early events causing muscle injury have been obtained from mechanical studies (Lieber & Fride!n 1993, Warren et al. 1993) as well as immunohistochemical studies of cellular and extracellular proteins (Lieber et al. 1996). From these ...

Hepatologists, gastroenterologists and alcohol researchers throughout the world were deeply saddened to learn of the death of Dr Charles Saul Lieber on 1 March 2009. Dr Lieber died at his home in Englewood Cliffs, NJ, at the age of 78. Charles Lieber was the father of modern alcohol research: he was a pioneer and giant in the field starting to investigate the effects of alcohol on the liver as ...