Nearly 50 % of newly diagnosed colorectal cancer, affect people over 70 years of age. Inclusion of older patients in clinical trials has been extremely rare. As a result, there is debate on how to manage these patients because it is still unclear how to balance the therapeutic advantages and toxicities. For patients who do not have comorbid conditions, with performance status (P.S.) 0–1, treatm...

A functional relationship between two variables, applied mass to a weighing platform and estimated mass using Multi-Layer Perceptron Artificial Neural Networks is approximated by a linear function. Linear relationships and correlation rates are obtained which quantitatively verify that the Artificial Neural Network model is functioning satisfactorily. Estimated mass is achieved through recallin...

Polynomials are much beloved by mathematicians but are of limited value for modeling measured data. Natural processes often display linear trends, and occasionally a constant acceleration process exhibits quadratic variation. However , higher-order polynomial behavior is rare in nature, which is more likely to produce exponentials, sinusoids, logistics , Gaussians, or other special functions. M...

In research disciplines such as organization science and information systems, fit, for example between environmental factors and organizational structure, and between organizational tasks and information systems, plays an important role to explain and predict variables such as organizational performance and user satisfaction. We build on the observation that while different types of fit have be...

Custom-made and off-the-shelf functional knee orthoses from four manufacturers were evaluated. Anterior tibial translation testing was performed using a pneumatic mechanical surrogated knee. The mechanical surrogate was interfaced with a servohydraulic materials testing system, which applied all anterior/posterior displacements to an ultimate anterior load of 400 N. Comparison of the individual...

Model evaluation is one of the most important aspects of structural equation modeling (SEM). Many model fit indices have been developed. It is not an exaggeration to say that nearly every publication using the SEM methodology has reported at least one fit index. Most fit indices are defined through test statistics. Studies and interpretation of fit indices commonly assume that the test statisti...

Projects have been in existence since time immemorial. The simplest definition of a project, as an engagement with constraints, usage resources order to achieve specified goal and scope work be performed qualifies the building pyramids projects. Research has endeavoured put project concept clear perspective well identify various theories upon which rides. Across organizations also projects exis...

We discuss fitting hadronic Green functions versus time t to extract mass values in quenched lattice QCD. These data are themselves strongly correlated in t. With only a limited number of data samples, the method of minimising correlated χ 2 is unreliable. We explore several methods of modelling the correlations among the data set by a few parameters which then give a stable and sensible fit ev...