Background: Chronic myelogenous leukemia (CML) is a myeloproliferative disorder due to BCR-ABL1 translocation. Patients showing transformation into blast crisis (BC) have poorer treatment response and prognosis.  Methods: A retrospective study was conducted in the department of Pathology, Maulana Azad Medical College, New Delhi, India, over a time period of 5 years (2014-2019) to evaluate the ...

In the paper, we show that lineage data collected during the processing and analysis of datasets can be reused to perform selective reprocessing (at sub-image level) on datasets while the remainder of the dataset is untouched, a rather difficult process to automate without lineage.

Background: One important reproductive characteristic of Mammals is the production of milk to nurse the neonate. In order to better understand the evolution of milk we have investigated gene expression in milk cells from monotremes which are the most ancient representative of the mammalian lineage. Materials and Methods: Using a milk cell cDNA sequencing approach we characterise milk protein se...

Incomplete lineage sorting (ILS), modelled by the multi-species coalescent, is a process that results in a gene tree being different from the species tree. Because ILS is expected to occur for at least some loci within genome-scale analyses, the evaluation of species tree estimation methods in the presence of ILS is of great interest. Performance on simulated and biological data have suggested ...

background menstrual blood-derived stem cells (menscs) are a novel source of stem cells that can be easily isolated non-invasively from female volunteered donor without ethical consideration. these mesenchymal-like stem cells have high rate of proliferation and possess multi lineage differentiation potency. this study was undertaken to isolate the menscs and assess their potential in differenti...

background:â there is a relationship between specific genotypes of helicobacter pylori caga and vaca genes and the increased risk of peptic ulcer diseases and gastric cancer. these genes also possess strong patterns of geographical differentiation. the present study aims to determine the patterns of variation of the virulence genes in iran and their association with clinical status. materials a...

The concept of celebrities has shaped societies throughout history. This work addresses the problem of celebrity identification from social media interactions. “Celebritiness” is a characteristic assigned to persons that are initially based on specific achievements or lineage. However, celebritiness often transcends achievements and gets attached to the person itself, causing them to capture po...

objective(s):from the ancient era, emergence of agriculture in the connecting region of mesopotamia and the iranian plateau at the foothills of the zagros mountains, made iranian gene pool as an important source of populating the region. it has differentiated the population spread and different language groups. in order to trace the maternal genetic affinity between iranians and other populatio...

This paper examines intergenerational relations in Taiwan with a major focus on how the relations between second and third generations may be affected by prior family experiences between first, second and third generations. As a typical patriarchal family system, lineage differences regarding the effects of three-generation households on intergenerational relations are explored. Panel data from...

A real-time qPCR assay was designed to detect African-derived subspecies of western honey bees (Apis mellifera L.). The probes targeted the same region mitochondrial cytochrome b gene used in previous restriction enzyme assays. Using samples from 16 A. representing four lineages, we evaluated efficacy this identify African- (or A-lineage) and non-A-lineage bees. successfully differentiated A-li...