Because nevi share risk factors with melanoma and are strong risk factors for melanoma, they are suitable biomarkers for evaluating sun protection programs. Kidskin was a trial of a school-based sun protection program in Western Australia that included high and moderate intervention groups and a control group. Schools were assigned nonrandomly to groups. The primary outcome was number of nevi o...

Because nevi share risk factors with melanoma and are strong risk factors for melanoma, they are suitable biomarkers for evaluating sun protection programs. Kidskin was a trial of a school-based sun protection program in Western Australia that included high and moderate intervention groups and a control group. Schools were assigned nonrandomly to groups. The primary outcome was number of nevi o...

Benign pigmented skin lesions are very common in children and can be generally classified into congenital or acquired nevi. Congenital nevi can be small, medium or large. Large nevi are usually associated with a higher risk of malignant transformation into melanoma. Acquired melanocytic nevi can be classified into typical melanocytic nevi, clonal nevi, or halo nevi. Cytological atypia can be ob...

BACKGROUND Currently, there is disagreement as to whether speckled lentiginous nevi (nevi spili) are congenital or acquired pigmented lesions. Part of this controversy is related to the natural history of these lesions that often present at birth as hyperpigmented patches and then take several years to reach their more readily recognized spotted form. Arguments in favor of speckled lentiginous ...

The mechanisms for the development of acquired melanocytic nevi remain mostly unclear. Here we report a case of eruptive nevi that developed after localized superficial trauma, and review the currently known cellular and triggering factors for acquired melanocytic nevi. A 66-year-old woman presented a linear arrangement of pigmented macules on her left calf that developed after a bloodless skin...

1. Sugarman JL. Epidermal nevus syndromes. Semin Cutan Med Surg. 2007;26:221-30. 2. Solomon LM, Fretzin DF, Dewald RL. The epidermal nevus syndrome. Arch Dermatol. 1968;97:273-85. 3. Solomon LM, Esterly NB. Epidermal and other congenital organoid nevi. Curr Provi Pediatr. 1975;6:1-56. 4. Singal A, Dhaliwal U, Bhattacharyya SN , Rohatgi J, Singh N. Complex ocular choristomas in linear nevus seba...

Verrucous epidermal nevi ― hamartomas of keratinocyte or appendages, located on the skin mucous membranes in form isolated birthmarks, less often have a linear localization. The pathogenesis verrucous has not been fully defined, probably development disease is associated with genetic mutations during embryogenesis and represent special mosaicism. are pathologies that require attention as potent...

Verrucous epidermal nevi are hamartomatous lesions of the epidermis that, unlike other epidermal nevi (such as sebaceous nevus or nevus comedonicus), are rarely associated with malignant neoplasms. The majority of squamous cell carcinoma develop in linear or multiple epidermal nevus and rarely in solitary epidermal nevus. In general, the prognosis is favorable. We report a case of well-differen...

The mast cells participate in inflammation and possibly in carcinogenesis. The aim of the study was to study mast cells in melanocytic lesions. The material consisted of 24 pigmented nevi, 18 dysplastic nevi and 19 melanomas. The sections were stained immunohistochemically for tryptase and chymase. Positive cells were counted inside the lesions and at the interface between the lesion and dermis...