The Linear Non-Threshold (LNT) process is used by virtually all governmental agencies to compute incidence of cancer as a consequence of exposure to a carcinogen. This comment applies the concept of Best Available Science (BAS) Metrics for Evaluation of Scientific Claims (MESC) derived from BAS to issues related to reliability of LNT hypothesis. This paper identifies the level of maturity of th...

INTRODUCTION. It is commonly stated that " any radiation dose, no matter how small, can cause cancer ". The basis for that statement is the linear-no threshold theory (LNT) of radiation carcinogenesis. According to LNT, if 1 Gy (100 rads) of exposure gives a cancer risk R, the risk from 0.01 Gy (1 rad) of exposure is R/100, the risk from 0.00001 Gy (1 millirad) is R/ 100,000, and so on. Thus th...

OBJECTIVE Nuclear medicine technologists work under significant radiation protection constraints. These constraints are based on the linear no-threshold (LNT) radiation paradigm, which was developed in the 1960s and was based largely on the deleterious effects of radiation as they were understood at the time. More recently, the theory of radiation hormesis, or a beneficial effect of low-level e...

The prime concern of radiation protection policy since 1959 has been protecting DNA from damage. The 1995 NCRP Report 121 on collective dose states that since no human data provides direct support for the linear no threshold hypothesis (LNT), and some studies provide quantitative data that, with statistical significance, contradict LNT, ultimately, confidence in LNT is based on the biophysical ...

The linear no-threshold (LNT) dose-effect relationship has been consistently used by most radiation epidemiologists to estimate cancer mortality risk. The large scattering of data by International Agency for Research on Cancer, IARC (Vrijheid et al. 2007; Therry-Chef et al. 2007; Cardis et al. 2007), interpreted in accordance with LNT, has been previously demonstrated (Fornalski and Dobrzyński ...

Organisms survive best, or show high fitness, in the habitats in which they most commonly occur, a phenomenon referred to as hormesis in the literature of toxicology. Examples of hormesis accumulate rapidly in the literature. However, a lack of underlying models has led many to doubt its existence, especially for ionizing radiation. The evolutionary model developed here indicates that all poten...

It is not true that successive groups of researchers from academia and research institutions-scientists who served on panels of the US National Academy of Sciences (NAS)-were duped into supporting a linear no-threshold model (LNT) by the opinions expressed in the genetic panel section of the 1956 "BEAR I" report. Successor reports had their own views of the LNT model, relying on mouse and human...

Some Areas of Ramsar, a city in northern Iran are among the world’s wellknown inhabited areas with highest levels of natural radiation. Annual exposure levels in these areas are up to 260 mGy y‐1 and the mean exposure rate is about 10 mGy y‐1 for a population of about 2000 residents. If elevated levels of natural radiation as high as a few hundred mSv per year is detrimental to health and...