Linum spp. from section Syllinum are promising for the production of aryltetralin lignans like podophyllotoxin (PTOX) and 6-methoxypodophyllotoxin (MPTOX). MPTOX is a PTOX congener that has cytotoxic activity comparable with PTOX. In this study root cultures of Linum Bungei from section Dasyllinum, L. strictum from section Linastrum, L. album, L. mucronatum ssp. mucronatum and L. nodiflorum fro...

The archaeological evidence of flax cultivation dates back to >6000 BC and it is considered as one of the oldest and most useful crops. Components of flax have diverse uses. Cultivar development of flax is currently focused on enhancing the oil content and nutritional value to meet the demand of nutraceutical market supply, as an alternate source of fish oil, a rich source of eicosapentaenoic a...

Spores of arbuscular mycorrhizal (AM) fungus Funneliformis mosseae (Nicolson & Gerdemann) Walker & Schuessler were cultured in association with transformed roots of Linum usitatissimum L. (Linaceae) for the first time on modified Strullu-Romand medium (pH 5.5) in monoxenic culture. Germ tubes emerged through the spore wall in 88% of spores after 5 days. Hyphal contact with transformed linum roo...

We investigate patterns of genetic variation along an east-west transect of Central European populations of Linum flavum and interpret the Quaternary history of its peripheral populations, especially those at the westernmost isolated range edge, discussing their migrations and possible relict status. We defined our peripheral transect across three study regions from Central Hungary, eastern Aus...

Linum flavum hairy root lines were established from hypocotyl pieces using Agrobacterium rhizogenes strains LBA 9402 and ATCC 15834. Both strains were effective for transformation but induction of hairy root phenotype was more stable with strain ATCC 15834. Whereas similar accumulation patterns were observed in podophyllotoxin-related compounds (6-methoxy-podophyllotoxin, podophyllotoxin and de...