background: phthalates are a group of multifunctional chemicals. diethyl phthalate (dep) is one of the most frequently used phthalates in solvents and fixatives for numerous industrial products. method: the present experiment was designed to assess oxidative stress, if any, caused by diethyl phthalate. for this the homogenates of liver and kidney were treated with different concentrations ( 10-...

Elasticity measurements of bilayer lipid membranes (BLM) based on registration of the third harmonic of the membrane current during the application of a periodic tension to the membrane was used to study the effects of lipid peroxidation (LPO) and phospholipase A on BLM. LPO resulted in decreased values of the Young modulus for BLM, while some products of LPO and phospholipid hydrolysis (linole...

in order to find a prophylactic supplementation for individuals who are at risk of exposure to ionizing radiation, we attempted to evaluate the effect of vitamin e (vit-e), a biological free radical scavenger, on restoration of hepatic lipid peroxidation (lpo) and lipid profile (lp) changes induced by sublethal g- radiation in balb/c mice. the concentrations of cholesterol and phospholipid were...

Oxidative stress and lipid peroxidation (LPO) accompanying infections and chronic inflammation may induce several human cancers. LPO products are characterized by carbohydrate chains of different length, reactive aldehyde groups and double bonds, which make these molecules reactive to nucleic acids, proteins and cellular thiols. LPO-derived adducts to DNA bases form etheno-type and propano-type...

BACKGROUND Many tissues play an important role in metabolic homeostasis and the development of diabetes and obesity. We hypothesized that the circulating redox metabolome is a master metabolic regulatory system that impacts all organs and modulates reactive oxygen species (ROS) production, lipid peroxidation, energy production and changes in lipid turnover in many cells including adipocytes. ...

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Oxidative stress plays an important role in the pathogenesis of neurodegenerative diseases, such as Parkinson's disease (PD). There are several methods to measure oxidative stress, being lipid peroxidation (LPO) one of the most frequently used. Endogenous plasma LPO was determined by a spectrofluorimetric method in fifty two patients with sporadic PD and in forty controls. To know the maximum c...

Submit Manuscript | http://medcraveonline.com Abbreviations: DM: Diabetes Mellitus; CVDs: Cardiovascular Diseases; PQQ: Pyrroloquinoline Quinone; LDH: Lactate Dehydrogenase; RR-value: Relative Risk Value; LPO: Lipid Peroxidation; LOOH: Lipid Hydroperoxide; HDL-C: High Density Lipoprotein; ROS: Reactive Oxygen Species; MDA: Malondialdehyde; STZ: Streptozotocin; PBS: Phosphate Buffered Saline; BS...

The effects of agricultural chemicals on cortisol secretion, antioxidants, and lipid peroxidation were investigated in hepatic and adrenal tissue of white sucker (Catostomus commersoni) from a river (Yamaska) that drains an agricultural region in Québec (Canada). Plasma cholinesterase (ChE) activity, used as a biomarker of exposure to pesticides, was elevated in fish from the reference site com...

The new indicator for lipid peroxidation (LPO) processes--9-hydroxy-10,12-octadecadienoic acid (9-HODE)--was used to investigate, whether LPO processes are increased in destructed bone material of patients suffering from rheumatoid arthritis (RA) in comparison to surrounded non destructed bone material. The HODE content in destructed bones exceeded that of non destructed ones of the same patien...