نتایج جستجو برای: lipid peroxidation malondialdehyde meta
تعداد نتایج: 330227 فیلتر نتایج به سال:
In this study, we investigated the role of nitric oxide metabolism and lipid peroxidation in patients with P. vivax malaria. The levels of nitrite and nitrate were analyzed using a procedure based on the Griess reaction and malondialdehyde levels which index of lipid peroxidation was determined by thiobarbituric acid reaction. The levels of nitrite/nitrate and malondialdehyde in patients were h...
BACKGROUND AND PURPOSE Oxidative stress has been postulated to account for delayed neuronal death due to ischemia/reperfusion. We investigated cerebral formation of malondialdehyde as an index of lipid peroxidation in relation to different sources of reactive oxygen species in patients undergoing carotid endarterectomy. METHODS In 25 patients undergoing carotid endarterectomy, jugular venous-...
The study was designed with an aim to evaluate the antiperoxidative potential of ascorbic acid on flutamide-induced lipid peroxidation. The study was performed in vitro using goat liver as lipid source. This evaluation was done by measuring the malondialdehyde and reduced glutathione content of the tissue as markers of lipid peroxidation. The study reveals the lipid peroxidation induction capac...
Oxidative stress plays an important contributory role in the pathogenesis of age-related chronic diseases. Increased lipid peroxidation process is caused by an enhanced free radical formation together with a higher supply of substrates and by an insufficient defense by antioxidants as well. Levels of malondialdehyde to content of lipid peroxidation substrates (polyunsaturated fatty acids), prom...
background: the association between lipid peroxidation biomarkers and adipocytokines is hypothesized in preeclampsia but little is known about it. objective: the present study was undertaken to determine the association of lipid peroxidation biomarkers measured by the levels of 8-isoprostane and malondialdehyde with adipocytokines leptin and adiponectin in maternal serum of preeclamptic women. ...
Acaciaside A and B, two acylated triterpenoid bisglycosides isolated from the funicles of Acacia auriculiformis, are known to have antihelmintic activity. Since the saponins contain a conjugated unsaturated system that is highly susceptible to peroxidation, we investigated the interaction of saponins and membrane using rat liver microsomes as our model. Microsomal membranes were incubated with ...
Lipid peroxidation products like malondialdehyde, 4-hydroxynonenal and F(2)-isoprostanes are widely used as markers of oxidative stress in vitro and in vivo. This study reports the results of a multi-laboratory validation study by COST Action B35 to assess inter-laboratory and intra-laboratory variation in the measurement of lipid peroxidation. Human plasma samples were exposed to UVA irradiati...
OBJECTIVE To assess and compare the status of lipid peroxidation, both in control subjects and in coronary heart disease patients. METHODS Serum total cholesterol, triglycerides, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol and malondialdehyde levels were determined in 46 patients with coronary heart disease and 50 age matched control healthy subjects. 29 male cor...
The present study deals with exploration of lipid peroxidation induction capacity of cyclophosphamide, an anticancer drug, and in vitro evaluation of ascorbic acid as a suppressor of cyclophosphamide induced lipid peroxidation. Goat liver homogenate has been used as the lipid source. This evaluation was done by measuring the malondialdehyde, 4-hydroxy-2-nonenal, reduced glutathione and nitric o...
The present study deals with exploration of lipid peroxidation induction capacity of flutamide, an anticancer drug, and in vitro evaluation of water extract of Spirulina platensis as a suppressor of flutamide-induced lipid peroxidation. Goat liver homogenate has been used as the lipid source. This evaluation was done by measuring the malondialdehyde and reduced glutathione content of the tissue...
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