نتایج جستجو برای: liver fibrosis
تعداد نتایج: 410943 فیلتر نتایج به سال:
Background and Aim: Methotrexate (MTX) is commonly used in the treatment of diseases such as rheumatoid arthritis (RA) but, its hepatotoxicity potential, always has been a major concern. The aim of this study is to determine the rate of liver fibrosis by transient elastography (TE) method and its relationship with cumulative dose of MTX and duration of treatment, in rheumatoid arthritis patient...
Purpose: To study the effect of allogenic bone marrow mesenchymal stem cells (BMMSCs) transplantation on carbon tetrachloride-induced liver fibrosis in mice. Materials and Methods: Fifty five female NMRI mice were divided in 5 groups, and to induce liver fibrosis CCL4 intraperitonealy was injected 1ml/Kg twice a week for 8 weeks 106 allogenic BMMSCs were infused in cell therapy group via tail v...
Background & Aim: Viral hepatitis has existed since the creation of human. The estimated prevalence of hepatitis is about 3-5%. For patients with chronic hepatitis C and moderate to severe liver fibrosis, antiviral therapy is strongly suggested, while the cases without fibrosis or with mild liver fibrosis are often followed up without receiving antiviral therapy. The purpose of the present s...
Objective: To assess Methotrexate-related side effects on the liver. Patients & methods: 45 liver biopsies were examined in dermatology ward of Loghman-e-Hakim Hospital in 1986-91.27 liver biopsies were examined after treatment with Methotrexate and were comparisoned with 27 liver biopsies which were not treated with Methotrexate. Results: Among 27 liver biopsies which were treated with...
conclusions erα expression in liver was inversely correlated with liver fibrosis among patients infected with chronic hcv genotype 1b. patients and methods all the consecutive patients who received the same standard treatment protocol for hcv genotype 1b were subdivided into two subgroups according to their fibrosis scores as fibrotic stages < 2 in mild fibrosis group and fibrotic stages ≥ 2 in...
background hepatic fibrosis is an inclusion indicator for treatment and a major independent predictor of treatment response in patients with chronic hepatitis c. liver biopsy, considered as the “gold standard” for evaluating liver fibrosis, has carried some drawbacks. currently used noninvasive predictors of fibrosis are considered less accurate than liver biopsy. objectives our aim was to asse...
introduction and aims: impact of treatment on progression of fibrosis in autoimmune hepatitis (aih) is unknown. we assessed the changes in liver fibrosis before and after treatment among these patients. materials and methods: nineteen aih patients who had paired liver biopsies were studied. of these, seven had been treated with 6 months of cyclosporine-a and the rest with 6 months of prednisolo...
background hepatic fibrosis is a typical complication of chronic liver diseases resulting in cirrhosis that remains a major public health problem worldwide. liver biopsy is currently the gold standard for diagnosing and staging hepatic fibrosis. percutaneous liver biopsy; however, is an invasive procedure with risks of complications. therefore, there is need for alternative non-invasive techniq...
liver involvement in iranian children with cystic fibrosis: ultrasonography and biochemical findings
results abnormal liver function test was detected in cf patients. as well, liver sonogram was abnormal in approximately one-third of the patients. this study showed a higher prevalence of biochemical abnormality in patients with abnormal livers ultrasonography. conclusions noninvasive paraclinical evaluation methods could be recommended in the patients with cf for early detection of silent live...
conclusions hcv coinfection, older age and ast were associated with lf in patients with hiv infection. objectives the aim of this cross-sectional study was to identify factors associated with liver fibrosis (lf) in patients with hiv monoinfection and hiv-hcv coinfection. patients and methods we analyzed lf by transient elastometry ([te], fibroscan) in three groups of patients (hiv, hiv-hcv and ...
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