background: human embryonic stem cells (hesc), which are derived from the inner cell mass of the blastocysts, have been considered to be pluripotent cells. in this study we examine the differentiating potential of hesc into hepatocytes by characterization of the expression of endoderm and liver-specific genes. methods: hesc were cultivated in suspension to form aggregates, the embryoid bodies. ...

Objective(s): Stem cell therapy is believed to be as a promising treatment strategy for tissue repair and regeneration. The plasticity specification of the adult stem cells, such as MSCs, has enabled that these cells to be used in the treatment of a broad spectrum of diseases like liver disorders. In this study, the production of urea and Albumin (Alb), glycogen storage, and expression of some ...

Background: Human embryonic stem cells (hESC), which are derived from the inner cell mass of the blastocysts, have been considered to be pluripotent cells. In this study we examine the differentiating potential of hESC into hepatocytes by characterization of the expression of endoderm and liver-specific genes. Methods: hESC were cultivated in suspension to form aggregates, the embryoid bodies. ...

Effects of Phoenix dactylifera extract and testosterone enanthate with without resistance training on MFN2, FISS DRP1 genes expression in liver rat

Background: Although Escherichia coli (E. coli)is a part of intestinal normal microflora of warm-blooded animals, includingpoultry, outbreaks occur in poultry raised below standard sanitation and duringthe course of respiratory or immunosuppressive diseases. Avian pathogenic E.coli (APEC) harbors several genes associated with virulence andpathogenicity. APEC strains are responsible for some dis...

MicroRNAs has been shown to regulate lipogenesis in liver. The aim of the present study was to investigate whether the effects of resveratrol (RSV) on lipogenesis is associated with the changes in the expression of two miRNAs (miR-107 and miR-10b) that regulate lipogenic pathways. 30 wild type C57BL/6j male mice were randomly fed three diets: a standard chow diet (ND), a high fat diet (HFD, 60%...

MicroRNAs has been shown to regulate lipogenesis in liver. The aim of the present study was to investigate whether the effects of resveratrol (RSV) on lipogenesis is associated with the changes in the expression of two miRNAs (miR-107 and miR-10b) that regulate lipogenic pathways. 30 wild type C57BL/6j male mice were randomly fed three diets: a standard chow diet (ND), a high fat diet (HFD, 60%...

The Effect of Valproic Acid Drug on the Expression SOCS1, SOCS3, JAK1, JAK2, STAT3, STAT5A and STAT5B Genes in HepG2 Cell Line Liver Cancer

Effects of Resveratrol Supplementation and Exercise on Apoptosis, Lipid Profile, Expression Farnesoid X Receptor, Liver Receptor Sirtuin 1 Genes in the Type Diabetic Rats

objective(s):fuzheng huayu recipe (fzhy) exerts significant protective effects against liver fibrosis by strengthening the body’s resistance and removing blood stasis. however, the molecular mechanisms through which fzhy affects liver fibrosis are still unclear. in this study, we examined the expression levels of factors involved in the inhibitor κb kinase-β (ikk-β)/nuclear factor-κb (nf-κb) an...