Cytophagic histiocytic panniculitis is a rare disease, associated with either nonmalignant conditions or subcutaneous panniculitis-like T-cell lymphoma, and often also associated with hemophagocytic lymphohistiocytosis (HLH). We report the case of a 11-year-old boy with a history of secondary HLH who, after a local trauma, developed a painful, indurated plaque over the right thigh associated wi...

Sir, Pancreatic panniculitis (PP) is a rare disease that is caused by the massive release of pancreatic enzymes into the bloodstream and results in cytosteatonecrosis of the hypodermis. PP is clinically characterized by painful or asymptomatic nodules of the legs that closely resemble erythema nodosum or infectious panniculitis (1). The nodules may sometimes spontaneously ulcerate and drain bro...

Cytophagic histiocytic panniculitis (CHP) was first described in 1980. It classically presents with intermittent recurrent episodes of pyrexia subcutaneous nodules, pancytopenia and liver dysfunction, but most patients have in addition a multitude of other manifestations which confuse the clinical picture. Despite the variable clinical course, the disease is often fatal. Diagnosis is based on h...

A 33 year old man developed fever, malaise, jaundice, pancytopenia, coagulation abnormalities, hepatomegaly, pleural effusions and a subcutaneous lump. Biopsies revealed a lobular panniculitis with the presence of cytophagic histiocytes; erythrophagocytosis was also demonstrated in the liver and bone marrow. Despite the use of chemotherapy (CHOP) his clinical condition deteriorated and he died ...

The authors present an unusual case of lobular panniculitis caused by Borrelia burgdorferi senso latu infection in a 56-year-old man. It presented clinically as a solitary subcutaneous nodule. Histopathologically, the lesion resembled subcutaneous panniculitis-like T-cell lymphoma by manifesting atypically appearing lymphocytes with cytotoxic phenotype. B. burgdorferi etiology was proven by pos...

BACKGROUND Pancreatic panniculitis is a rare complication of pancreatic disease occurring in 2% to 3% of all patients, most commonly those with acute or chronic pancreatitis. MAIN OBSERVATIONS We report the case of a pancreatic panniculitis associated with acute pancreatitis in a 63-year-old man. He presented with a 2-day history of multiple tender subcutaneous nodules, followed by nausea, vo...

We describe a case of a 40-year-old woman who presented with ecchymoses of the right leg and who was found to have lobular panniculitis in biopsy due to Munchausen's Syndrome.

BACKGROUND Erythema induratum of Bazin is a mostly lobular panniculitis. There is considerable controversy in the literature about whether or not vasculitis is a histopathologic requirement to establish the diagnosis of erythema induratum of Bazin. Even accepting vasculitis as a histopathologic criterion, there is no agreement about the nature and size of the involved vessels. OBJECTIVE The m...