the present study investigated the possibility of replacing salamon with modified shotor diluent (msd) and egg yolk (ey) with low density lipoprotein (ldl) for chilled storage of ram semen. good quality semen (>80% progressive forward motility (pfm) of sperm) from 3 fertile rams was collected using an artificial vagina and pooled for each experiment. low density lipoprotein was extracted from f...

accumulating evidence suggest that in patients with diabetes mellitus, increased rate of lipoprotein oxidation and oxidative stress have important role in diabetic angiopathy, including nephropathy. to evaluate the association of oxidized low- density lipoprotein (ox-ldl) with the development of diabetic nephropathy, plasma level of ox-ldl were measured in 70 diabetic patients with macro and 63...

liver secretes a large range of very low density lipoprotein (vldl) particles of different sizes and svedberg flotation rates (sf). in plasma vldl is converted to low density lipoprotein (ldl)which in turn plays an important role in the development of atherosclerotic diseases; however,triglyceride (tg) rich vldl1 has been shown to be more deleterious than cholesteryl ester (ce) rich vldl2. ther...

background: vascular calcification is an important stage in atherosclerosis. during this stage, vascular smooth muscle cells (vsmc) synthesize many osteogenic factors such as osteonectin (encoded by sparc). oxidative stress plays a critical role in atherosclerosis progression, and its accumulation in the vascular wall stimulates the development of atherosclerosis and vascular calcification. the...

background: oxidative modification of low-density lipoprotein (ldl) appears to be an early step in the pathogenesis of atherosclerosis. meanwhile, myeloperoxidase (mpo)-catalyzed reaction is one of the potent pathway for ldl oxidation in vivo. the aim of this study was to evaluate in vitro antioxidant effects of vitamins c and e on ldl oxidation mediated by mpo. methods: mpo was isolated from f...

antioxidant consumption has been reported to be inversely associated with the incidence of coronary artery disease. to clarify the possible role of vitamin e and volatile oils in the prevention of atherosclerosis, the effects of these compounds on the susceptibility of low-density lipoprotein (ldl) to oxidative modification were investigated. in this study, vitamin e and seven volatile oils “an...

background: a great deal of evidence has indicated that oxidatively modified ldl plays a critical role in the initiation and progression of atherosclerosis. antioxidants that can prevent ldl oxidation may act as antiatherogens. copper is a candidate for oxidizing ldl in atherosclerotic lesions. the binding of copper ions to ldl is usually thought to be a prerequisite for ldl oxidation by copper...

introduction this paper proposes the concept of autonomous drug-encapsulated nanoparticle (adenp) as a novel non-invasive approach to prevent atherosclerosis. adenp consists of three simple units of sensor, controller (computing), and actuator. the hardware complexity of adenp is much lower than most of the nanorobots, while the performance is maintained by the synergism in the swarm architectu...

background: elevated serum levels of oxidized low-density lipoprotein (oxldl) have been found in type 2 and in poorly controlled diabetic patients. gestational diabetes mellitus (gdm) has common features with type 2 diabetes. objective: the aim of our study was to evaluate the serum levels of oxldl in women with gdm compared to normal pregnant women. materials and methods: in this cross-section...

the non-enzymatic carbamylation of low density lipoprotein (ldl) is a naturally occurring chemical modification of apolipoprotein b as a result of condensation between lysine residues and cyanate derived from urea. carbamylated ldl is poorly recognized by ldl receptors and initiates different processes that can be considered proatherogenic. thus, ldl carbamylation may contribute to the increase...