نتایج جستجو برای: low dose interferon
تعداد نتایج: 1503914 فیلتر نتایج به سال:
BACKGROUND Despite advances in the staging and surgical therapy of melanoma, patients with high-risk resected melanoma still have 5-year recurrence rates of 55% to 80% and 5-year survival rates as low as 25% to 70%. Effective adjuvant therapy is needed for this patient population. METHODS The authors review the literature regarding the use of interferon for the adjuvant therapy of resected me...
bronchiolitis has been known as one of the pathological features of lung injuries in mustard gas exposed patients the purpose of this research was to evaluate the efficacy of interferon gamma-1b on the lung function in mustard gas exposed patients with bronchiolitis. in multicenter research interferon gamma-1b was effective in pulmonary fibrosis with unknown reason, but assessment of effect of ...
conclusion we constructed and validated a ct colonography phantom with correct density allowing performance of reproducible experiments. materials and methods we found 15 different phantom designs by literature search and compared their advantages and disadvantages based on their description and images. we tested various materials for density and mechanical properties and constructed a phantom ...
Several adverse effects have been associated with interferon alpha 2b treatment and neuropsychiatric effects have also been commonly reported. Psychosis and mood disorders have been described in the literature. This case report is of a 30 year old man with malignant melanoma stage 3a who was receiving adjuvant alpha 2b interferon and developed a manic episode two weeks post switching after one ...
Cytomegalovirus (CMV) infection has been associated with the development of myocarditis in humans. Our established mouse model for CMV myocarditis allows detailed investigation of the immunopathogenic mechanisms and therapies for cardiovascular disease. The type I interferons (IFN-alpha/beta) are part of the innate immune response to CMV infections. Previously, we have reported that daily treat...
A series of anthraquinones with amino substituents at the 1,5 positions were found to induce interferon in mice. A prototype compound, 1,5-bis[(3-morpholinopropyl)amino]-anthraquinone (Ia), was an effective antiviral agent when administered either orally or parenterally. Peak interferon titers were found 12 to 24 h after drug treatment. The minimum oral dose of Ia required to induce serum inter...
BACKGROUND There is some controversy concerning the efficacy of low dose alpha interferon therapy in chronic hepatitis C. AIMS To evaluate the effectiveness of treatment with low doses of alpha interferon in chronic hepatitis C. PATIENTS One hundred and forty one patients with anti-HCV positive chronic active hepatitis C from six hospitals were enrolled in the study. METHODS Patients were...
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