It is important to minimize lung dose during intensity-modulated radiation therapy (IMRT) of nonsmall cell lung cancer (NSCLC). In this study, an approach was proposed to reduce lung dose by relaxing the constraint of target dose homogeneity during treatment planning of IMRT. Ten NSCLC patients with lung tumor on the right side were selected. The total dose for planning target volume (PTV) was ...

The study is to investigate a Hybrid IMRT/VMAT technique which combines intensity modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) for the treatment of nonsmall cell lung cancer (NSCLC). Two partial arcs VMAT, 5-field IMRT, and hybrid plans were created for 15 patients with NSCLC. The hybrid plans were combination of 2 partial arcs VMAT and 5-field IMRT. The dose d...

Purpose: This study aims to evaluate the treatment plans of Volumetric-modulated arc therapy (VMAT) and intensity-modulated radiation (IMRT) techniques for cervical-thoracic esophageal cancers. Methods and Materials: Sixty patients were retrospectively identified. Several parameters evaluated based on target conformity and dose-volume histograms organs at risk (lung, spinal cord, heart). A ...

Purpose: The purpose of this study is to analyze and compare the dosimetric parameters of three dimensional conformal radiotherapy (3DCRT) and intensity modulated radiotherapy (IMRT) in selected non-small cell lung cancer (NSCLC) cases. Methods: Ten patients with inoperable NSCLC were selected for this study. The 3DCRT and IMRT plans were generated for all patients following Radiation Therapy O...

Aim: To dosimetrically compare and evaluate Intensity Modulated Radiation Therapy (IMRT) versus conventional five field radiotherapy (5FCRT) in postmastectomy radiotherapy (PMRT). Material and Methods: This study included 25 consecutive patients for PMRT. Target volumes (chest wall, axilla, supraclavicular regions [SCF]) and normal structures (lungs, heart, spinal cord, opposite breast) were de...

BACKGROUND The optimal technique for performing lung IMRT remains poorly defined. We hypothesize that improved dose distributions associated with normal tissue-sparing IMRT can allow safe dose escalation resulting in decreased acute and late toxicity. METHODS We performed a retrospective analysis of 82 consecutive lung cancer patients treated with curative intent from 1/10 to 9/14. From 1/10 ...

The clinical use of respiratory-gated radiotherapy and the application of intensity-modulated radiotherapy (IMRT) are 2 relatively new innovations to the treatment of lung cancer. Respiratory gating can reduce the deleterious effects of intrafraction motion, and IMRT can concurrently increase tumor dose homogeneity and reduce dose to critical structures including the lungs, spinal cord, esophag...

In this study, we assess the dosimetric qualities and usability of planning for 1.5 T MR-Linac based intensity modulated radiotherapy (MRL-IMRT) various clinical sites in comparison with IMRT plans using a conventional linac. total 30 patients disease brain, esophagus, lung, rectum vertebra were re-planned retrospectively simulated MRL-IMRT Elekta Unity dedicated treatment system (TPS) Monaco (...

BACKGROUND Cure rate of early Hodgkin Lymphoma are high and avoidance of late toxicities is of paramount importance. This comparative study aims to assess the normal tissue sparing capability of intensity-modulated radiation therapy (IMRT) versus standard three-dimensional conformal radiotherapy (3D-CRT) in terms of dose-volume parameters and normal tissue complication probability (NTCP) for di...

PURPOSE A study was performed comparing dosimetric characteristics of volumetric modulated arcs (RapidArc, RA) and fixed field intensity modulated therapy (IMRT) on patients with bilateral breast carcinoma. MATERIALS AND METHODS Plans for IMRT and RA, were optimised for 10 patients prescribing 50 Gy to the breast (PTVII, 2.0 Gy/fraction) and 60 Gy to the tumour bed (PTVI, 2.4 Gy/fraction). Ob...