BACKGROUND This study aimed to test the hypothesis that alteration of left ventricular (LV) torsional mechanics occurs in patients after repair of tetralogy of Fallot (TOF) and is associated with right ventricular (RV) volume overload and changes in LV configuration. METHODS AND RESULTS Fifty-five TOF patients aged 19.0 ± 8.1 years and 27 age-matched healthy controls were studied. The LV and ...

The contractile state of the left ventricle in man was analyzed by correlating left ventricular (LV) dimensional changes during contraction determined from cineangiograms, with simultaneous measurements of LV pressure. The mechanical characteristics of ventricular contraction were expressed quantitatively by deriving the extent and velocity of circumferential fiber shortening at the midwafl and...

Several studies have shown associations of high levels of hemoglobin (Hgb) or blood viscosity with cardiac events and with left ventricular (LV) hypertrophy (LVH). To assess the relations of LV mass and function with Hgb delivery (ie, the physiological carrier of oxygen), we calculated the product of Hgb concentration and Doppler-derived cardiac output in 864 hypertensive participants with elec...

background: several echocardiographic markers have been introduced to assess the left ventricular (lv) mechanical dyssynchrony. we studied dyssynchrony markers and the latest lv activation site in heart failure patients with and without left bundle branch block (lbbb). methods: conventional echocardiography and tissue velocity imaging were performed for 78 patients (lv ejection fraction ≤ 35%),...

conclusions lv twist, torsion and untwist and also rate of them are significantly impaired in dcm and this impairment is well-related to lv global systolic and diastolic dysfunction. vvi is a new noninvasive technique that can be used to evaluate lv torsional parameters. results lv twist value (5.54 ± 1.94° in dcm vs. 11.5 ± 2.45° in control group) and also lv torsion (0.71 ± 0.28°/cm in dcm vs...

AIMS Remodelling of the left ventricle (LV) is associated with adverse cardiovascular events, but the mechanisms of these effects remain undefined. We investigated the relationship of LV mass and geometry to LV function in a large cohort of hypertensive subjects. METHODS AND RESULTS We studied 1074 hypertensive individuals without cardiovascular disease recruited from the London Life Sciences...

BACKGROUND Conventional Doppler parameters are unreliable for estimating left ventricular (LV) filling pressures in hypertrophic cardiomyopathy (HCM). This study was undertaken to evaluate flow propagation velocity by color M-mode and early diastolic annular velocity (Ea) by tissue Doppler 2 new indices of LV relaxation, combined with mitral E velocity for estimation of filling pressures in HCM...

BACKGROUND Poor glycemic control is associated with impaired left ventricular (LV) diastolic function in patients with type 2 diabetes mellitus (T2DM). Inappropriate LV mass increase and accelerated aortic stiffening were suggested to participate on deterioration of diastolic function. The present study investigated the inter-relationships between glycemic control, early diastolic and systolic ...

OBJECTIVES We studied the effects of LV unloading by the Impella on coronary hemodynamics by simultaneously measuring intracoronary pressure and flow and the derived parameters fractional flow reserve (FFR), coronary flow velocity reserve (CFVR), and coronary microvascular resistance (MR). BACKGROUND Patients with compromised left ventricular (LV) function undergoing high-risk percutaneous co...

conclusions results suggest that these methods cannot be interchanged, and vvi showed significantly lower lv peak twist, peak twisting rate and peak untwisting rate. however, when lv twist and lv twisting rates were normalized to lv length, values were comparable for both imaging techniques. results twist degree was significantly lower in the vvi group than in the tdi group (p = 0.008, r = 0.56...