نتایج جستجو برای: lymphatic diseases

تعداد نتایج: 862288  

2012
Shintaro Nakao Ali Hafezi-Moghadam Tatsuro Ishibashi

Lymphatic is a prerequisite for the maintenance of tissue fluid balance and immunity in the body. A body of evidence also shows that lymphangiogenesis plays important roles in the pathogenesis of diseases such as tumor metastasis and inflammation. The eye was thought to lack lymphatic vessels except for the conjunctiva; however, advances in the field, including the identification of lymphatic e...

Journal: :Thrombosis and haemostasis 2007
Ruediger Liersch Michael Detmar

The lymphatic vascular system plays an important role in the maintenance of fluid homeostasis, in the afferent immune response, in the intestinal lipid uptake and in the metastatic spread of malignant cells. The recent discovery of specific markers and growth factors for lymphatic endothelium and the establishment of genetic mouse models with impairment of lymphatic function have provided novel...

Journal: :Journal of the American Medical Association 1914

Journal: :JCI insight 2017
Florence Tatin Edith Renaud-Gabardos Anne-Claire Godet Fransky Hantelys Francoise Pujol Florent Morfoisse Denis Calise Fanny Viars Philippe Valet Bernard Masri Anne-Catherine Prats Barbara Garmy-Susini

Lymphatic endothelium serves as a barrier to control fluid balance and immune cell trafficking to maintain tissue homeostasis. Long-term alteration of lymphatic vasculature promotes edema and fibrosis, which is an aggravating factor in the onset of cardiovascular diseases such as myocardial infarction. Apelin is a bioactive peptide that plays a central role in angiogenesis and cardiac contracti...

پایان نامه :دانشگاه آزاد اسلامی - دانشگاه آزاد اسلامی واحد علوم دارویی - پژوهشکده علوم 1392

purpose a metabolic abnormality such as obesity is a major obstacle in the maintenance of the human health system and causes various chronic diseases including type 2 diabetes, hypertension, cardiovascular diseases, as well as various cancers. this study was designed to summarize the recent scientific knowledge regarding the anti-obesity role of curcumin (diferuloylmethane), which is isolated f...

Journal: :Investigative ophthalmology & visual science 2011
Hui Zhang Xuemei Hu Julie Tse Firehiwott Tilahun Mengsheng Qiu Lu Chen

PURPOSE Lymphatic dysfunctions are associated with many diseases, ranging from cancer metastasis to transplant rejection, for which there is little effective treatment. To date, there is no natural model with which to study lymphatic regression. This study was conducted to investigate whether murine cornea, an extensively exploited tissue for vascular studies, derives its lymphatic-free status ...

2014
Germaine D. Agollah Manuel L. Gonzalez-Garay John C. Rasmussen I-Chih Tan Melissa B. Aldrich Chinmay Darne Caroline E. Fife Renie Guilliod Erik A. Maus Philip D. King Eva M. Sevick-Muraca

The lymphatic vasculature plays a critical role in a number of disease conditions of increasing prevalence, such as autoimmune disorders, obesity, blood vascular diseases, and cancer metastases. Yet, unlike the blood vasculature, the tools available to interrogate the molecular basis of lymphatic dysfunction/disease have been lacking. More recently, investigators have reported that dysregulatio...

Journal: :Development 2016
Jonathan Semo Julian Nicenboim Karina Yaniv

The lymphatic system is a blind-ended network of vessels that plays important roles in mediating tissue fluid homeostasis, intestinal lipid absorption and the immune response. A profound understanding of the development of lymphatic vessels, as well as of the molecular cues governing their formation and morphogenesis, might prove essential for our ability to treat lymphatic-related diseases. Th...

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