Central nervous system (CNS) aspergillosis is a severe disease that responds poorly to current therapies. The current studies examined the efficacies of several antifungal agents alone or in combination with a murine model of CNS aspergillosis. Immunosuppressed mice were infected intracerebrally with Aspergillus fumigatus and treated with an amphotericin B preparation, an echinocandin, or voric...

The pan-European MacroBen database was used to compare the AZTI Marine Biotic Index (AMBI) and the Benthic Quality Index (BQIES), 2 biotic indices which rely on 2 distinct assessments of species sensitivity/tolerance (i.e. AMBI EG and BQI E[S50]0.05) and which up to now have only been compared on restricted data sets. A total of 12 409 stations were selected from the database. This subset (indi...

Background and Purpose—Diffusion-weighted imaging (DWI) is superior to conventional MRI in identification of small new ischemic lesions and discrimination of recent infarcts from old ones. Thus, this technique is useful in the detection of acute multiple brain infarcts (AMBI). We sought to determine the frequency and the topographical and etiologic patterns of AMBI detected on DWI. Methods—We s...

BACKGROUND AND PURPOSE Diffusion-weighted imaging (DWI) is superior to conventional MRI in identification of small new ischemic lesions and discrimination of recent infarcts from old ones. Thus, this technique is useful in the detection of acute multiple brain infarcts (AMBI). We sought to determine the frequency and the topographical and etiologic patterns of AMBI detected on DWI. METHODS We...

The Mahanadi Estuarine System (MES), with a complex network of freshwater channels, rivers, and mangroves, is leading seaport in State Odisha on the east coast India, but subjected to intense human activity recent years. Such anthropic impingements are known impact sediment-dwelling biota adversely. However, information macrobenthic community MES not well documented yet. Therefore, primary obje...

The Gulf of Mexico (GoM) is an economically important region (e.g. oil and gas, fisheries) with the expansion drilling, harmful algal bloom events, blowouts, dead zones, anthropogenic eutrophication contaminant loading, it that ecological quality statuses (EcoQS) different localities in are closely monitored. EcoQS, as implemented by European Water Framework Directive, effective tool for monito...