In the study conducted to determine prevalence of placental malaria burden in Anambra State, Nigeria, venous and placenta blood samples were collected from 254 pregnant women screened a cross-sectional hospital – based survey. Malaria parasitaemia was diagnosed by microscopy while anaemia defined as haemoglobin concentration <12g/l. species typed using thin film parasite morphology count. Of...

Abstract Background Malaria is endemic in sub-Saharan Africa, and oxidative stress has been implicated malaria disease. Luffa cylindrica an ethnomedicinal plant used to treat various diseases, including malaria. The stress-reducing potential of L. malaria-disease state Plasmodium berghei NK-65 parasite-infected mice was carried out vivo. Materials Methods Mice were infected with P. NK-65, the e...

Background: Falciparum malaria is a severe health burden worldwide. Antigen presenting cells are reported to be affected by erythrocytic stage of the parasite. Malarial hemozoin (HZ), a metabolite of malaria parasite, has adjuvant properties and may play a role in the induction of immune response against the parasite. Objective: To determine the immunological impact of hemozoin on the capacity ...

background: this study aimed at determining the prevalence and associated risk factors for asymptomatic malaria parasitaemia and anemia among blood donors in a private medical laboratory in benin city, nigeria. methods: venous blood was collected from a total of 247 blood donors. malaria status, abo, rhesus blood groups and hemoglobin concentration of all participants were determined using stan...

background: this study aimed at determining the prevalence of malaria and anemia among child­ren in rural community of okada, edo state nigeria, as well as to assess the level of use of insecti­cide treated bed nets and its impact on prevalence of malaria and anemia among study population. methods: thick blood films from 226 children with signs and symptoms of malaria in okada commu­nity were s...

1. The screening for potential anti-malaria properties by bioassay guided fractionations. The biological properties were carried out using the plasmodium lactate dehydrogenase assay (pLDH) (Makler, 1993). 2. The harmful effect of the extract was determined by the MTT assay (Mossman, 1983). 3. The extracts were tested for its efficacy in animal model using rodent malaria parasite, P. berghei usi...

1. The screening for potential anti-malaria properties by bioassay guided fractionations. The biological properties were carried out using the plasmodium lactate dehydrogenase assay (pLDH) (Makler, 1993). 2. The harmful effect of the extract was determined by the MTT assay (Mossman, 1983). 3. The extracts were tested for its efficacy in animal model using rodent malaria parasite, P. berghei usi...