نتایج جستجو برای: malonyl coenzyme a decarboxylase

تعداد نتایج: 13436944  

Journal: :Journal of bacteriology 2001
N Smirnova K A Reynolds

The Streptomyces glaucescens beta-ketoacyl-acyl carrier protein (ACP) synthase III (KASIII) initiates straight- and branched-chain fatty acid biosynthesis by catalyzing the decarboxylative condensation of malonyl-ACP with different acyl-coenzyme A (CoA) primers. This KASIII has one cysteine residue, which is critical for forming an acyl-enzyme intermediate in the first step of the process. Thre...

Journal: :The Journal of biological chemistry 2004
Aneta E Reszko Takhar Kasumov France David Katherine R Thomas Kathryn A Jobbins Jie-Fei Cheng Gary D Lopaschuk Jason R B Dyck Mireya Diaz Christine Des Rosiers William C Stanley Henri Brunengraber

The goal of this study was to test the relationship between malonyl-CoA concentration and its turnover measured in isolated rat hearts perfused with NaH(13)CO(3). This turnover is a direct measurement of the flux of acetyl-CoA carboxylation in the intact heart. It also reflects the rate of malonyl-CoA decarboxylation, i.e. the only known fate of malonyl-CoA in the heart. Conditions were selecte...

Journal: :Journal of Biological Chemistry 1960

Journal: :molecular biology research communications 2013
durdi qujeq mohsen tatar farideh feizi hadi parsian sohrab halalkhor

malonyl-coa decarboxylase (mcd) is an enzyme involved in the decarboxylation of malonyl-coa to acetyl-coa. in order to explore the hypothesis that the changing plant materials’ mcd activity level can serve as therapy to diabetics, the effect of teucrium polium compounds was studied in a diabetic rat model. in this experimental study, two groups of rats, a control and a diabetic group, each incl...

Journal: :The Journal of biological chemistry 1985
Y S Kim S K Bang

Malonyl coenzyme A synthetase (EC 6.2.1.14) was induced in Pseudomonas fluorescens grown on malonate as a sole carbon source. This enzyme was purified, for the first time, over 30-fold by the combination of ammonium sulfate precipitation, Sephadex G-150 gel filtration, DEAE-Sephacel ion exchange chromatography, and hydroxylapatite chromatography. The purified enzyme, which had a specific activi...

Journal: :Science 2007
Liangcai Gu Todd W Geders Bo Wang William H Gerwick Kristina Håkansson Janet L Smith David H Sherman

An unexpected biochemical strategy for chain initiation is described for the loading module of the polyketide synthase of curacin A, an anticancer lead derived from the marine cyanobacterium Lyngbya majuscula. A central GCN5-related N-acetyltransferase (GNAT) domain bears bifunctional decarboxylase/S-acetyltransferase activity, both unprecedented for the GNAT superfamily. A CurA loading tridoma...

Journal: :Journal of Biological Chemistry 1968

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