twik2 ion channels (k2p6.1, encoded by a gene named kcnk6) belong to the family of two-pore domain potassium channels. twik2 is also considered as a “silent” channel because of its inability to produce measurable currents in heterologous expression systems and its intracellular retention. it is expressed in different mammalian tissues including lymphoid organs and the vascular system. however, ...

Background: Mammalian preimplantation development is a complex process involving dramatic changes in the transcriptional architecture. However, it is still unclear about the crucial transcriptional network and key hub genes that regulate the proceeding of preimplantation embryos. Materials and Methods: Through single-cell RNAsequencing (RNA-seq) of both human and mouse preimplantation embryos, ...

the objective of this study was to describe the seroprevalence rates of bluetongue virus (btv) in sheep in west and northwest provinces of iran. bluetongue virus, an economically important orbivirus of the reoviridae family, causes a hemorrhagic disease mainly in sheep and occasionally in cattle and some species of deer. bluetongue virus is transmitted between its mammalian hosts by certain spe...