Only ash remains after fire is gone. Metaphorically mania is the fire and depression its ash (Koukopoulos & Ghaemi 2009). What is the reason, when there is just fire without ash? Unipolar mania has been described in the literature. Different terms have been used like recurrent mania, chronic mania and persistent mania. But these are scarce diagnoses in psychiatric routine. This topic has got li...

We wished to determine whether decreases in prefrontal glutamate concentrations occur in offspring of parents with bipolar disorder with and at high risk for mania. Sixty children and adolescents, 9-18 years old, of parents with bipolar I or II disorder (20 offspring with established history of mania, "BD", 20 offspring with symptoms subsyndromal to mania, "SS", and 20 healthy controls "HC") we...

OBJECTIVE To develop a reliable and valid parent-report screening instrument for mania, based on DSM-IVsymptoms. METHOD A 21-item Child Mania Rating Scale-Parent version (CMRS-P) was completed by parents of 150 children (42.3% female) ages 10.3 +/- 2.9 years (healthy controls = 50; bipolar disorder = 50; attention-deficit/hyperactivity disorder [ADHD] = 50). The Washington University Schedule...

BACKGROUND There is considerable debate surrounding the effective measurement of DSM-IV symptoms used to assess manic disorders in epidemiological samples. METHOD Using two nationally representative datasets, the National Epidemiological Survey of Alcohol and Related Conditions (NESARC, n=43,093 at wave 1, n=34,653 at 3-year follow-up) and the National Comorbidity Survey - Replication (NCS-R,...

BACKGROUND AND OBJECTIVES Phenomenological studies on mood disorder are rare in Nepal which prompted us to undertake the current factor analytical study of mania. MATERIALS AND METHODS It was a cross-sectional descriptive study for which we did purposive sampling technique according to certain inclusion and exclusion criteria. The study sample consists of fifty patients, who fulfilled the Int...

objective: the purpose of this study was to evaluate the effect of adjunctive topiramate in treating acute mania. methods: in this study which was a double-blinded randomized clinical trial, 46 bipolar patients in manic episode, were treated with lithium carbonate and topiramate versus lithium carbonate and placebo and treatment responses were assessed by young mania rating scale (ymrs) weekly....

BACKGROUND Impulsivity is elevated among people diagnosed with bipolar disorder, and recent evidence suggests that impulsivity can predict onset among those at risk for the disorder. Impulsivity, though, is a broad construct. OBJECTIVE The goal of this study was to examine whether some aspects of impulsivity are more correlated with risk for mania than others. We hypothesized that risk for ma...

Mania due to tricyclic antidepressant use has been well reported in literature but reports of SSRI's induced mania are less. This case reports a sertraline induced mania and discusses the use of this drug in adolescent females.

The association between suicidality and diagnoses of mixed mania, as defined using both DSM-IV and Cincinnati criteria, was studied in 576 consecutive manic inpatients. Of the whole sample, 51 (8.9%) had suicidal ideation and 13 (2.3%) attempted suicide during the index episode. Suicidality was significantly more frequent in patients with a diagnosis of mixed mania, whether the diagnosis was ma...