This study examined the effect of sensory feedback (e.g., flashing lights and sound) on the imitation performance of children with autism and typical children group-matched for mental age. Participants were administered an immediate object-imitation task with six novel toys constructed for this study: three with a sensory effect that could be activated by imitating the modeled action and three ...

Phospholipase A2 (sPLA2), pivotal for allergic and inflammatory response, hydrolyses phosphatidylcholine (PC) to lysophosphatidylcholine (LPC). In present study, the role of LPC in allergic airway disease manifestation was studied using mouse model. Balb/c mice were immunized using cockroach extract (CE) and LPC release was blocked by sPLA2 inhibitor. Airway hyperresponse (AHR), lung-histology,...

OBJECTIVE To report the results of open challenge tests performed in children fed with cow's milk-free diet. DESCRIPTION Cross-sectional study evaluating cow's milk open challenge performed under supervision in a hospital setting during 2.5 hours and ambulatory follow-up for 30 days when no immediate reaction occurred. One hundred and twenty-one patients were included, with ages between 4 and...

Actinic keratosis represents the earliest manifestation of non-melanoma skin cancer. Because of their risk of progression to invasive squamous cell carcinoma, an earlier diagnosis and treatment are mandatory. Their diagnosis sometimes could represent a challenge even for expert dermatologists. Dermoscopy, confocal laser microscopy and optical coherence tomography could help clinicians in diagno...

One manifestation of the “Big Knowledge’’ challenge is providing automated tools for summarization of ontology content to facilitate user comprehension. An aggregation approach for the automatic identification and display of major subjects covered by an ontology’s content is presented. The results show that our methodology is viable in capturing the “big picture” of ontology content.

A negative flecainide challenge does not rule out Brugada syndrome even in the presence of nonfatal cardiac arrest as the first manifestation of the disease. This should prompt clinicians to ensure long-term ECG follow-up and consider repeating a drug test with another sodium channel blocker.

The recent article by Snowden et al (1) is illuminating but does not mention the close relationship between late-life depression and Alzheimer’s disease. Late-life depression may actually be an early manifestation of Alzheimer’s disease itself. Failure to recognize subtle signs and symptoms can delay appropriate treatment, which is a major challenge in effectively treating depression in the eld...

Ocular lesions are a common manifestation of toxoplasmosis in cats. In this survey, 10 healthy Syrianmice were infected through intraperitoneal inoculation of bradyzoites of Toxoplasma gondii (Tehran strain).Mice were killed 30 days after inoculation and the suspension of their brains was prepared, after confirmationof the infection. Seven kittens were fed with the infected mice brain suspensio...