autoimmunity and viral infections are closely associated fields, and viruses have been proposed as a likely aetiological, contributory or triggering factors of systemic autoimmune diseases. hepatitis c virus seems to be the virus usually associated with the appearance of autoimmune diseases, and the relationship between chronic hepatitis c virus infection and some autoimmune disease has been st...

the present study was conducted on sixty healthy female domestic ruminants that suffered from still births or abortion, to find sero-positive cases and also to determine the probable role of uterine tissue in diagnosis of akabane viral infection and viral persistency. because of this, a serological test (elisa) and molecular (rt-pcr) diagnostic methods were used to find the seropositive cases a...

in order to adapt lasota strain of newcastle disease virus (ndv) on chick embryo fibroblast (cef) cells, 0.1 ml from lasota vaccine produced in razi vaccine and serum research institute inoculated to the cef cells and was passaged five times in the cef grown in eagle’s minimum essential medium (mem). first to third passages were blind but in fourth passage cytopathic effect of virus was observe...

background & aim: the recent study was conducted to investigate the effects of thyme extract in drinking water on immune response of broiler chickens. experimental:  a total of 245 day-old broiler chicks were purchased and 20 chicks were bled for determination maternal antibody and remaining chicks divided into 5 equal groups. chickens of group a, b and c received 0.1%, 0.15% and 0.2% ofthy...

introduction: quantification of epstein - barr virus (ebv) in peripheral blood mononuclear cells (pbmnc) of allogenic bone marrow transplant (bmt) recipients is important because ebv-associated posttransplant lymphoproliferative disease (ptld) can occur after transplantation due to immunosup-pression therapy. methods: to this end we chose real-time pcr using taqman probe. for the standard curve...

orf is a mucocutaneous disease that occurs when non-intact skin comes into contact with contaminated sheep saliva. the lesions may complicate to lymphangitis or secondary bacterial infection, but systemic complications such as erythema multiforme, maculopapular rash, and generalized lymphadenopathy are rare. in this paper, we present two cases of erythema multiforme following orf disease.

in this study, immunohistochemistry was used to clarify the early stages of viral kinetics and cycliccourse of ibdv, ir499, which has been described earlier as a very virulent strain (vvibdv). fifteen, 4-week-old spf chickens were inoculated with 10³ eid50 of vvibdv, ir499, via oculo/nasal route. five birdsserved as controls, and inoculated with phosphate buffered saline (pbs). the birds were t...

epstein-barr virus (ebv) was discovered 50 years ago from an african burkitt lymphoma cell line. ebv-associated lymphoproliferative disorders (lpds) are life-threatening diseases, especially in children. in this article, we review ebv-associated lpds, especially in the area of primary immunodeficiency disease (pid). we searched pubmed for publications with key words including ebv infection, lym...

newcastle disease virus (ndv) was isolated and identified for the first time from a flock of japanese quail suspected to nd in iran. birds of the flock aged variously, and some of them died from the disease. loss of appetite, weakness and decrease in egg production, diarrhea and nervous symptoms were the main clinical signs in the birds. hemorrhagic lesions of the intestinal tracts and proventr...

the pathogenicity of a recent isolate of infectious bursal disease virus (ibdv), ir499, isolated from a nonvaccinated flock with 17.5 % mortality rate in susceptible spf chickens, chickens embryos and broilers was discussed. the molecular characterization of the virus based on the restriction fragment length polymorphism (rflp) pattern was also investigated. the mortality rates were 85% and 22%...