S.-K. Kim Specialized Graduate School & Technology Convergence, Department of Marine-Bio Convergence Science, Marine Bioprocess Research Center, Pukyong National University, Yongdong Campus, 365, Sinseon-ro, Nam-gu, Busan 608-739, Republic of Korea e-mail: [email protected] Abstract Natural products provide an important source of new therapeutic drugs and biochemical tools. In the last decades ...

The present work describes the biological activities using the marine sponges collected from kanyakumari. The sponges are such as the Callyspongia diffusa, Echinodictyum gorgonoides, Callyspongia reticutis, Gelliodes cellaria, and Thalysias vulpine. It is revealed that the sponges showed the antifungal activity against the various fungal strains such as the Aspergillus niger, Pencillium notatum...

Unlike filamentous fungi and bacteria, very little is known about cultivable yeasts associated with marine sponges, especially those from Antarctic seas. During an expedition to King George Island, in the Antarctica, samples of 11 marine sponges were collected by scuba-diving. From these sponges, 20 psychrotolerant yeast isolates were obtained. Phylogenetic analyses of D1/D2 and ITS rRNA gene s...

Marine sponges are primitive metazoans that produce a wide variety of molecules that protect them against predators. In studies that search for bioactive molecules, these marine invertebrates stand out as promising sources of new biologically-active molecules, many of which are still unknown or little studied; thus being an unexplored biotechnological resource of high added value. Among these m...

Marine sponges (Porifera) have attracted significant attention from various scientific disciplines. Remarkable traces, left by sponges in the fossil records have been studied by paleontologists and evolutionary biologists. As sponges produce various novel chemical molecules, they have been a goldmine to chemists and also found their way into biotechnological applications. Microbiologists became...

SYNOPSIS. Secondary metabolites are widespread among lower phyla and understanding their functional role(s) in the producing organism has been under study in recent decades. Considerable progress has been made in understanding chemical ecological interactions among terrestrial organisms, and similar research in the marine realm has been initiated in recent years. Polar regions are more difficul...

conclusions our results suggest that h. parva and h. oculata may be promising therapeutic candidates for the treatment of hcc, following further confirmatory in vivo experiments and clinical trials. results our results showed that h. parva methanolic extracts (250, 500, and 1000 µg/ml) and h. oculata methanolic extracts (200, 400, and 800 µg/ml) increased reactive oxygen species (ros) formation...

Nature, especially the marine environment, provides the most effective drugs used in human therapy. Among the metazoans, the marine sponges (phylum Porifera), which are sessile filter feeders, produce the most potent and highly selective bioactive secondary metabolites. These animals (or their associated symbiotic microorganisms) synthesize secondary metabolites whose activity and selectivity h...

the potential of marine actinobacteria particularly streptomyces as a single cell protein (scp) feed for the growth of ornamental fish, xiphophorus helleri has been investigated. the streptomyces strains used as scp were isolated from the marine sponges, namely callyspongia diffusa , mycale mytilorum , tedania anhelans and dysidea fragilis . six scp feeds were prepared and their effects were co...

Present review describes research on novel natural pharmacological compounds isolated from marine sponges. More than 90 novel cytotoxic antitumor compounds and their synthetic analogs have shown confirmed activity in vitro tumor cell lines bioassay and are of current interest to NCI for further in vivo evaluation. A great problem, to use directly the reservoir of marine organisms for therapy is...