In this article the differences between blood bank 8...'1d normal blood is shown. The danger of massive blood transfusion specially in shocked patient is discussed. The importance of warm blood, correction of acidosis with ventilation and bicarbonate, and the use of fresh plasma to compensate the reduction of coagulation factors are mentioned. The value of acid­phosphaite-dexterose (APD) as sto...

PURPOSE Massive blood transfusios are uncommon. The goal of this study was to propose an ideal ratio for the blood component of massive hemorrhage treatment after review of five years of massive transfusion practice, in order to have the best possible clinical outcomes. MATERIALS AND METHODS We defined a 'massive transfusion' as receiving 10 or more units of red blood cells in one day. A list...

Background The concept of massive transfusion was developed to trigger clotting factor therapy for the treatment of coagulopathy due to dilution, after a certain number of units of packed red blood cells. It has been defined as the replacement of circulating volume or the transfusion of more than 6 or 10 units of packed red blood cells (PRBC) in the 24 hours after injury. Until recently there h...

Blood transfusion represents the first and most prescribed cell-based therapy; however, clinical safety and efficacy trials are lacking. Clinical cohort studies have suggested that massive transfusion and/or transfusion of aged stored blood may contribute to multiorgan dysfunction in susceptible patients. In this issue of the JCI, Baek and colleagues report that aged stored blood hemolyzes afte...

The literature shows substantial data that acute coagulopathy and hemorrhage without rigorous resuscitative efforts has a high morbidity and mortality. The utilization of protocols for a massive transfusion and resuscitation can lead to improved outcomes in morbidity and mortality. Protocols for massive transfusion allow for improved access to blood components and delivery systems, improved tim...

BACKGROUND Hemorrhage in trauma is a significant challenge, accounting for 30% to 40% of all fatalities, second only to central nervous system injury as a cause of death. However, hemorrhagic death is the leading preventable cause of mortality in combat casualties and typically occurs within 6 to 24 hrs of injury. In cases of severe hemorrhage, massive transfusion may be required to replace mor...

background: acute normovolemic hemodilution is an available technique to decrease the side effects of allogenic blood transfusion. the aim of this study was to compare acute normovolemic hemodilution with allogenic blood transfusion in adult patients who were scheduled for femoral fracture surgery. methods: in this randomized controlled trial, 50 patients were randomly allocated into two equal ...

This study aimed to explore the correlation between red blood cell (RBC) transfusion volume and patient mortality in massive blood transfusion. A multicenter retrospective study was carried out on 1,601 surgical inpatients who received massive blood transfusion in 20 large comprehensive hospitals in China. According to RBC transfusion volume and duration, the patients were divided into groups a...