introduction: ischemic stroke is amongst the top four causes of mortality and the leading cause of disability in the world. the aim of this study was to evaluate the efficacy of a high dose memantine on neurological function of patients with ischemic stroke.methods: in a randomized, 2 armed, open-label study, patients with mild to moderate cerebral thromboembolic event (ctee) who admitted to im...

background: changes in the lipid profile have been suggested as a risk factor for developing ischemic stroke. their role in intra-cerebral hemorrhage, however, is not clear. the present study was designed to evaluate the lipid profile levels of patients who had experienced an acute stroke during the first 24-hour and to compare these levels in different patients suffering from the stroke, eithe...

background: the aim of this study was to evaluate whether higher serum levels of insulin-like growth factor-i (igf-i) in the acute phase of ischemic stroke are associated with less severe strokes and better functional outcome in a period of 12-month follow-up. methods: from october 2014 to august 2015, patients with the diagnosis of acute ischemic stroke admitted to the stroke unit of firoozgar...

background: stroke is the most common neurologic disease and an important cause of morbidity and mortality. headache is an initial presenting feature of ischemic stroke and sometimes preceedes the development of stroke and thus, provides an opportunity for offering preventive measures. the aim of the present study was to determine the association of new onset headache with stroke. methods: a to...

Objective: To evaluate low-molecular-weight (LMW) DNA as possible prognostic biomarker in acute ischemic and hemorrhagic stroke. Methods:  LMW DNA samples were isolated from plasma and cerebrospinal fluid by phenol deproteinization, analyzed by gradient polyacrylamide electrophoresis and quantified by spectrophotometry. Results: Two common types of the stroke, ischemic and hemorrhagic, differ...

We present the case of a patient with acute brain stem ischemic stroke who was found to have a fusiform basilar aneurysm with a thrombus within the dilated vessel. Three days after the ischemic stroke, the patient had a massive subarachnoid hemorrhage and died. This case illustrates the difficulties in the acute management of ischemic events in patients with basilar fusiform aneurysms, because ...

Background: Stroke is the third leading cause of mortality worldwide. One of the factors that affect the occurrence of stroke can be attributed to changes in the levels of trace elements. Accumulating evidence has been shown that magnesium, as an important element, is a new predictor of stroke. We aimed to determine the levels of Mg in ischemic stroke patients in comparison with those having th...

background: stroke is a leading cause of death all around the world, and ischemic stroke is considered to be the most common stroke type. toll-like receptors (tlrs) are important molecules for detection of both pathogen invasion and tissue damage. in this regard, the purpose of this study was to assess the expression level of tlr2 on monocytes in patients with ischemic stroke and to evaluate th...

background:  gender  difference  has  been   reported  in stroke  risk factors  and  disease  history. the aim  of this study  was  to  compare  risk factors  and  the  severity  of ischemic stroke based  upon  modified rankin scale (mrs) and hospital mortality between two genders. methods: in a  cross-sectional  study, 341  patients  (44% males and 56% females with a mean age of 68.94 ± 12.74 ...

increased levels of proinflammatory cytokines have been recorded after the onset  of transient  or  permanent  brain  ischemia and  are  usually associated with  exacerbation  of ischemic injury. embolic stroke model is more relevant to the pathophysiological situation in such  patients, because the  majority of  ischemic injuries in humans  are induced  by old thrombi that originate from the h...