PURPOSE To evaluate and compare real world cost-effectiveness of inhaled corticosteroids (ICS) administered by metered dose inhaler (MDI), breath-actuated MDI (BAI), or dry powder inhaler (DPI) in asthma. PATIENTS AND METHODS This retrospective database study analyzed the direct health care costs and proportion of patients (aged 5-60 years) achieving asthma control over 1 year in two populati...

Aims. To determine whether multiple daily injections (MDIs) or continuous subcutaneous insulin infusion (CSII) contributes to better glucose control in children with different type 1 diabetes duration. Methods. Subjects were grouped according to early (≤1 year after disease onset; 1A) or late (1-3 years after onset; 2A) MDIs/CSII treatment initiation. Corresponding control groups (1B, 2B) recei...

Delineating the processes that contribute to the progression and maintenance of substance dependence is critical to understanding and preventing addiction. Several previous studies have shown inhibitory control deficits in individuals with stimulant use disorder. We used a Bayesian computational approach to examine potential neural deficiencies in the dynamic predictive processing underlying in...

TAK-475 (lapaquistat acetate) and its active metabolite-I (TAK-475 M-I) inhibit squalene synthase, which catalyzes the conversion of farnesyl diphosphate (FPP) to squalene. FPP is a substrate for synthesis of other mevalonate-derived isoprenoids (MDIs) such as farnesol (FOH), geranlygeranyl diphosphate (GGPP), and geranylgeraniol. In patients with MKD, a rare autosomal recessive disorder, defec...

background : lack of insight in patients with bipolar i disorder has been associated with poor course and clinical outcome and compromised therapeutic compliance. therefore, it is important to evaluate insight and use more specialized scales such as mood disorder insight scale (mdis) in these patients. our objective in this study was to assess validity and reliability of persian version of mdis...

Background: Lack of insight in patients with bipolar I disorder has been associated with poor course and clinical outcome and compromised therapeutic compliance. Therefore, it is important to evaluate insight and use more specialized scales such as Mood Disorder Insight Scale (MDIS) in these patients. Our objective in this study was to assess validity and reliability of Persian version of MDIS....

BACKGROUND Lack of insight in patients with bipolar I disorder has been associated with poor course and clinical outcome and compromised therapeutic compliance. Therefore, it is important to evaluate insight and use more specialized scales such as Mood Disorder Insight Scale (MDIS) in these patients. Our objective in this study was to assess validity and reliability of Persian version of MDIS. ...

BACKGROUND Mini dental implants (MDIs) are becoming increasingly popular for rehabilitation of edentulous patients because of their several advantages. However, there is a lack of evidence on the osseointegration potential of the MDIs. The objective of the study was to histomorphometrically evaluate and compare bone apposition on the surface of MDIs and standard implants in a rabbit model. ME...

To determine the prescription characteristics of beta-agonist metered-dose inhalers (MDI), we retrospectively investigated all prescriptions containing one of five types of beta-agonist MDIs available at Yamagata University Hospital in 1997, as well as patients' characteristics. The total number of asthmatic patients was 225 (age, 11-79, mean, 47.2) in 1997. Fenoterol MDI was prescribed to pati...

The aim was to systematically review the efficacy of immediate loaded mini dental implants (MDIs) retain mandibular overdentures in regards survival rates MDIs, peri-implant clinical and radiographic tissue response associated factors. A literature search English performed using Google Scholar, Scopus, Web Science, MEDLINE (OVID), EMBASE, PubMed predetermined inclusion criteria. Specific terms ...