OBJECTIVE To identify risk factors for mortality in neonates with meconium aspiration syndrome. METHODS All neonates (2004-2010) with meconium aspiration syndrome, irrespective of gestation were included. Risk factors were compared between those who died and survived. RESULTS Out of 172 included neonates, 44 (26%) died. Mean (SD) gestation and birth weight were 37.9 (2.3) weeks and 2545 (64...

OBJECTIVE To assess the annual burden of early neonatal deaths associated with perinatal asphyxia in infants weighing ≥2500g in Brazil from 2005 to 2010. METHODS The population study enrolled all live births of infants with birth weight ≥2500g and without malformations who died up to six days after birth with perinatal asphyxia, defined as intrauterine hypoxia, asphyxia at birth, or meconium ...

This study (1) included one hundred and forty-one vigorous babies born through meconium stained amniotic fluid, of which 36.9% (52) babies developed respiratory distress. Of the 52 babies who developed respiratory distress 19.23%(10 babies) developed meconium aspiration syndrome (MAS). In this study, it was observed factors like caesarean section and thick meconium increased risk of respiratory...

Aspiration of meconium produces a syndrome (Meconium Aspiration Syndrome MAS) characterized by hypoxia, hypercapnia, and acidosis. Perinatal hypoxia, acute airway obstruction, pulmonary inflammation, pulmonary vasoconstriction, pulm­ onary hypertension, and surfactant inactivation all play a role in the pathogenesis of MAS. Most aspiration of meconium probably occurs before birth. Following asp...

meconium aspiration syndrome (maS) affects 0.43–2.1 in 1000 live births and can be life-threatening. a variety of treatment strategies is used, many of which do not have a solid evidence base to support them, but do appear to be effective. Routine suction of the fetal pharynx prior to delivery of the shoulders is not effective in reducing the incidence of maS and neither is routine suction of t...

At present time, delivery room management of babies born through Meconium stained amniotic fluid (MSAF) often includes suctioning of the mouth and nose before the delivery of the shoulders. This addresses the concern that babies will inhale meconium present in the upper airway with their first breath putting them at risk of MAS. The rationale of routine perineal suctioning of all babies born th...