Juvenile idiopathic arthritis (JIA) differs markedly from adult rheumatoid arthritis. It is not a single disease, but an exclusion diagnosis that gather together all forms of arthritis that begin before the age of 16 years, persist for more than 6 weeks, and are of unknown origin. The advent of the new biological treatments has dramatically changed both the observed responses to treatment and t...

The Jewish principle concerning a decision with regard to a dangerous treatment is as following: A patient who is estimated to die within 12 months because of a fatal illness is permitted to undergo a treatment that on the one hand may extend his life beyond 12 months, but on the other hand may hasten his death. There are, however, several limitations to this ruling related to the chances of su...

This paper deals with a special case of multicriteria optimization problems. The problems studied come from the medical domain and are of a very important practical relevance. One of the problems refers to the ranking of treatments for the Trigeminal Neuralgia. The second problem refers to a hierarchy of risk factors for Bronchial Asthma. The most common way to deal with a multiobjective optimi...