1. The degradative pathway of melamine (1,3,5-triazine-2,4,6-triamine) was examined in Pseudomonas sp. strain A. 2. The bacterium grew with melamine, ammeline, ammelide, cyanuric acid or NH+4 as sole source of nitrogen, and each substrate was entirely metabolized. Utilization of ammeline, ammelide, cyanuric acid or NH+4 was concomitant with growth. But with melamine as substrate, a transient in...

Cyanuric acid is able to form complementary hydrogen bonds with melamine. Here, the specific recognition between cyanuric acid and melamine is used to significantly improve the gene transfection efficacy of low generation dendrimers via a supramolecular approach.

Although the toxicity of melamine to the kidneys and testes is well known, few studies have investigated the effects of melamine on female reproductive organs. Therefore, this study explores the effects of oral administration melamine or melamine and cyanuric acid for 28 days on the ovaries of female rats. Rats that were exposed to the mixture exhibited reduced ovarian and uterine weights, a sh...

OBJECTIVES To study the migration of melamine into foods from plastic food packaging materials and dairy product containers commonly used in China. METHODS 37 samples were collected from the market. The EU migration testing conditions were adopted with distilled water, 3% acetic acid, n-hexane and 15% ethanol being chosen as the simulating solutions. The HPLC method was used to detect melamin...

Rhodococcus sp. strain Mel was isolated from soil by enrichment and grew in minimal medium with melamine as the sole N source with a doubling time of 3.5 h. Stoichiometry studies showed that all six nitrogen atoms of melamine were assimilated. The genome was sequenced by Roche 454 pyrosequencing to 13× coverage, and a 22.3-kb DNA region was found to contain a homolog to the melamine deaminase g...

The gene encoding melamine deaminase (TriA) from Pseudomonas sp. strain NRRL B-12227 was identified, cloned into Escherichia coli, sequenced, and expressed for in vitro study of enzyme activity. Melamine deaminase displaced two of the three amino groups from melamine, producing ammeline and ammelide as sequential products. The first deamination reaction occurred more than 10 times faster than t...

Melamine and its potential toxicity have drawn increased attention since a 2008 crisis in China in which milk, infant formula, and other foods were illegally laced with the chemical in order to increase their apparent protein content. That contamination affected an estimated 294,000 infants and children, with more than 50,000 hospitalizations and at least 6 deaths. In a new analysis of specific...

The impact of melamine-contaminated animal feed ingredients on food safety has become a major public concern ever since melamine was identified as the organic compound responsible for the deaths of a significant number of cats and dogs in 2007 by way of adulterated pet food. Melamine, a common industrial chemical often added to resins to improve flame resistance and proposed as an alternative f...

The structure of a 1:1 complex of uracil and melamine obtained by cocrystallization has been investigated. The structure involves hydrogen bonded layers with apertures stacked along the a and b directions giving rise to channels, unlike the complex of cyanuric acid with melamine.

Introduction......................................................................................................................... 1 Uses and possible human exposure ................................................................................... 2 Toxicity of Melamine .......................................................................................................... 2 Toxicity of ...