Introduction: Malignant melanoma is a fatal cutaneous neoplasm and one of the fastest growing cancers worldwide. The objective of this study is to evaluate the prevalence of melanoma in different cultural settings and the probable role of clothing for prevention. Materials and Methods: In this cross-sectional study, data about diagnosed melanoma patients in Kerman Province, Iran including age,...

herein we describe a case of intraocular melanoma in a17-year old leukemic patient.   the history, histological findings of the enucleated eye, blood and bone marrow of the patient were investigated. the enucleated eye contained epitheloid cell type melanoma instead of leukemic cell infiltration.  we conclude that intraocular malignant melanoma can occur in acute lymphoblastic leukemia.

background: malignant melanoma, one of the most deadly skin cancers, is a skin tumor that arises from the epidermal melanocytes. the aim of this study is to evaluate the demographic and clinical data of malignant melanoma patients in a referral dermatology center in the south of iran. methods: in this retrospective study, we have reviewed files of 116 patients diagnosed with malignant melanoma ...

introduction primary malignant esophageal melanoma makes up 0.1% to 0.2% of all esophageal malignancies. most physicians assume malignant melanoma as a skin originated neoplasm, however this type of melanoma can occur anywhere in the gastrointestinal tract especially in the esophagus. thus, it is essential to consider malignant melanoma in differential diagnosis of any esophagus masses. case pr...

gastrointestinal melanoma (gim) is occasionally observed in general practice. we report a case of melanoma dispersed diffusely in the stomach and duodenum with no skin involvement.

amelanotic melanoma is a variant of malignant melanoma comprising 2% to 8% of all malignant melanomas. the amelanotic presentation of melanoma in the oral cavity is extremely rare and has been reported only occasionally in the literature. moreover, the lack of melanin makes these tumors difficult to diagnose than that of pigmented lesions and the prognosis tends to be poorer. herein, we report ...

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Objective We have previously shown that Rose Bengal (RB) alone, not as a photosensitiser, could induce apoptotic- and non-apoptotic cell death in different melanoma cell lines. To clarify RB-induced toxicity mechanisms, role of caspases and reactive oxygen specious (ROS) were studied in melanoma cells. Material and Methods Human melanoma cell lines, Me 4405 and Sk-Mel-28 were cultured in DM...

background: anorectal melanoma is one of the rare but significant malignancies of the anorectal area. this malignancy currently accounts for 1% of all types of melanoma and less than 1% of all the anorectal area malignancies. very rare cases of this disease have been reported worldwide. anorectal melanoma is mostly diagnosed while treating other benign conditions of this area such as hemorrhoid...