malignant melanoma of the esophagus is a rare tumor with poor prognosis. the survival of patients is generally less than one year after diagnosis. a case of primary malignant melanoma of the esophagus is presented, who after radical resection of the tumor, is in excellent health, with no evidence of disease 14 months after surgery.

purpose: to report the clinical and histopathological features of recurrent atypical fibrous histiocytoma of the corneo-scleral limbus followed by intra-epithelial squamous neoplasia. case report: a 25-year-old female patient presented with a recurrent vascularized gelatinous mass in the left nasal limbus. the preliminary histopathological diagnosis of the previously excised lesion was an amela...

melanoma of the oral cavity is a rare malignant disease. on account of the presence at relatively obscure areas in the oral cavity, most of oral malignant melanomas are diagnosed at a late stage. early diagnosis is essential for successful treatment and perhaps is the key factor in improving the prognosis of oral malignant melanoma. however, no large clinical series exist, and in fact, clinical...

malignant melanoma has the heart metastasis rate of 50 - 71%, which seems to be the highest among other malignancies. when a patient presents with cardiac metastases of melanoma, the disease has already spread through the body and therefore hardly curable. this brief review tried to introduce this important condition and discuss its frequency, presentation, diagnosis, histologic findings and tr...

purpose: true neoplasm (adenocarcinoma) of retinal pigment epithelium (rpe) is very rare since it can be misdiagnosed as intraocular malignant melanoma it is of importance to know the clinical and pathologic aspects of this neoplasm. here, we report a case of adenocarcinoma of rpe. methods: case report. results: a 60-year-old man with progressive loss of the vision of the right eye was enucleat...

Melanocytic lesions constitute a very important topic in Pathology, not only for dermatopathologists but also for general pathologists. In this talk we will review how we apply immunohistochemistry as a tool to help in the differential diagnosis of melanocytic lesions. And we would like to stress that, as in other fields of pathology, immunohistochemistry should be considered as an adjunct to t...

Background & Objective: Malignant melanoma is the fatal cutaneous neoplasm which is curable by the early diagnosis. The expression of occludin protein which is an integral membrane protein is altered in an epithelial-to-mesenchymal transition. Although, recent studies provide sufficient evidence supporting the functional importance of occludin in cancer, the prognostic signific...