نتایج جستجو برای: melasma prevalence

تعداد نتایج: 279372  

2015
Juliana Kida Ikino Daniel Holthausen Nunes Vanessa Priscilla Martins da Silva Tania Silvia Fröde Mariana Mazzochi Sens

BACKGROUND Melasma is a chronic, acquired hyperpigmentation disease on sun-exposed areas of the skin, which affects patients' quality of life. OBJECTIVE To assess the impact on the quality of life of women living in Florianópolis, Brazil, through questionnaire (MelasQol), and investigate the clinical aspects and risk factors for melasma, correlating them with the MelasQol scores. METHODS Th...

Journal: :Journal of dermatological science 2007
En Hyung Kim You Chan Kim Eun-So Lee Hee Young Kang

BACKGROUND The pathogenesis of melasma is not yet fully understood. Previous studies indicate that dermal environment such as fibroblasts may have an important role in the development of melasma. Recently, it has been suggested that interactions between the cutaneous vasculature and melanocytes might have an influence on the development of pigmentation. OBJECTIVES We investigated the vascular...

2015
Shital Poojary Khushboo Minni

Melasma is a localized, chronic acquired hypermelanosis of the skin. Despite several treatments available, melasma can often be refractory to treatment. Also recurrences are common. Tranexamic acid is a new addition in treatment of melasma and is effective in dosage of 250 mg BD for atleast 4 to 8 weeks. Tranexamic acid acts mainly via the plasminogen activator-plasmin system to prevent UV radi...

Journal: :Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 1999
R M Manaloto T Alster

BACKGROUND Melasma is a facial dyspigmentation which is a common complaint in patients with darker skin tones. Many current therapies used for this condition are ineffective and can cause significant adverse effects. OBJECTIVE The purpose of this study was to evaluate the role of erbium:YAG laser resurfacing in the management of refractory melasma. METHODS Ten female patients with melasma u...

Journal: :iranian red crescent medical journal 0
hassan adalatkhah department of dermatology, ardabil university of medical sciences, ardabil, ir iran homayoun sadeghi bazargani department of statistics and epidemiology, tabriz university of medical sciences, tabriz, ir iran; department of statistics and epidemiology, tabriz university of medical sciences, tabriz, ir iran. tel: +98-9144027218, fax: +98-9144027218

background although, melasma is most prevalent among asian young women, and also darkly pigmented individuals are particularly prone to developing post inflammatory hyperpigmentation, to the best of our knowledge, there are rare or no studies about the association of melasma and post inflammatory hyperpigmentation. results we found out that 24.1% of patients without melasma had post-acne pigmen...

2015
Hassan Adalatkhah Homayoun Sadeghi-Bazargani

BACKGROUND Treatment of melasma is unsatisfactory most of the times. Hormonal role is shown to exist in pathogenesis of the melasma, and sex-hormone related drugs may have an effect on melasma. AIM To investigate efficacy of 1% flutamide cream versus 4% hydroquinone cream on melasma. METHODS In a parallel randomized clinical trial, 74 women with melasma were allocated to receive a sunscreen...

2016
Soon-Hyo Kwon Young-Ji Hwang Soo-Keun Lee Kyoung-Chan Park

Melasma is a commonly acquired hypermelanosis that affects sun-exposed areas of the skin, with frequent facial involvement. Its histologic manifestations are evident in the epidermis, extracellular matrix, and dermis. In addition to epidermal pigmentation, pathologic findings of melasma include extracellular matrix abnormality, especially solar elastosis. The disrupted basement membrane has bee...

2017
Emerson V. A. Lima Mariana Modesto D. A. Lima Mauricio Pedreira Paixão Hélio Amante Miot

BACKGROUND Melasma is a common chronic and relapsing acquired dyschromia. Skin microneedling was reported resulting sustained long-term improvement of recalcitrant melasma, however, the exact mechanism that promotes this skin lightening is not known. This study aimed to investigate clinical and histologic alterations promoted by skin microneedling in facial melasma. METHODS Open pilot trial i...

Journal: :Acta dermato-venereologica 2016
Nan-Hyung Kim Soo-Hyun Choi Tae Ryong Lee Chang-Hoon Lee Ai-Young Lee

Basement membrane (BM) disruption and dermal changes (elastosis, collagenolysis, vascular ectasia) have been reported in melasma. Although ultraviolet (UV) irradiation can induce these changes, UV is not always necessary for melasma development. Cadherin 11 (CDH11), which is upregulated in some melasma patients, has previously been shown to stimulate melanogenesis. Because CDH11 action requires...

Journal: :Journal of Investigative Dermatology 2022

Melasma is a common, chronic skin condition of hyperpigmentation involving the appearance symmetric and irregular light brown macules patches, mainly on sun exposed head neck. Though pathogenesis not fully understood, hyperfunctional melanocytes are known to deposit excess melanin in epidermis dermis. Known risk factors or triggers include genetic influence, hormonal ultraviolet radiation. Due ...

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