Aim of the study: To evaluate the antioxidant property of Smilax zeylanica L. using CCl4 hepatotoxicity in rats. Materials and methods: Hepatotoxicity was induced in Wistar albino rats by administration of CCl4 (0.5ml/kg/day p.o. for 7days). Methanol extract of S. zeylanica roots and rhizomes (SZRM) was administered to the experimental animals at doses 200,400 and 600 mg/kg/day, p.o. for 7 days...

The present study was conducted to evaluate the hepatoprotective activity of methanolic extract of aerial parts of Plumbago zeylanica in CCl4-induced hepatotoxicity in wistar rats. Silymarin (100mg/kg, p.o.) was given as reference drug. The extract of aerial parts of Plumbago zeylanica have shown very significant hepatoprotection against CCl4-induced hepatotoxicity in wistar rats by reducing se...

A reverse phase HPLC method with UV detection has been developed and validated in order to quantify plumbagin, the bioactive marker of the roots of P. indica and P. zeylanica. A quantitative HPTLC method was also developed using hexane: ethyl acetate (8:2) as the mobile phase. The plumbagin content in the roots were determined using both the methods. P. indica was found to contain significantly...

Plumbago zeylanica root has been used traditionally to treat various body ailments including liver diseases. The present study was designed to investigate the hepatoprotective effects of standardized methanolic extract of Plumbago zeylanica root on paracetamol, CCl4 and alcohol induced hepatic injuries in rats and its possible mechanism(s) of hepatoprotection. Administration of hepatotoxicants ...

Adhatoda zeylanica (Medic.) family-Acanthaceae is distributed all over the plains of India and lower Himalaya ranges, ascending to height of 1500 m. The present study is an attempt to explore the anti-inflammatory activity of ethanolic and aqueous extract of leaves of the Adhatoda zeylanica. Dose of 100 mg/ml and 200 mg/ml of ethanolic and aqueous extract were evaluated for their anti-inflammat...

Purpose: In the Ayurvedic system of medicine, Plumbago zeylanica is one of the important medicinal plants which possess several pharmaceutical activities such as antiplasmodial, anti-microbial, antitumour, hepatoprotective, antifungal, antiinflammatory and anticancer activity. It contains several active constituents and the most important bioactive compound is plumbagin which is a naphthoquinon...

The definition of methodologies for automatic ontology-based document annotation is a fundamental step in the Semantic Web vision. In the near future, semantic annotation services could become as important as search engines are today. Tools for the easy and effective development of such services are therefore needed. In this paper, we present Melita, a tool for the definition and development of...

A disease of Plumbago Zeylanica L. caused by Phoma exigua is reported for the first time from India.

The administration of Plumbago zeylanica root (50% EtOH) extract to |intact rats at the dose of 150 mg/kg [body weight for 60 days caused arrest of spermatogenesis. The diameter of seminiferous tubules and Leydig cell nuclei were reduced. The production of spermatocytes (primary and secondary) and spermatids were significantly reduced (P£ 0.001; 83.57%, 89.69% and 69.47% respectively). The tota...

Haze in the Klang Valley of Malaysia M. D. Keywood , G. P. Ayers, J. L. Gras, R. Boers, and C. P. Leong CSIRO Atmospheric Research, Australia Atmospheric Research Division, KNMI, The Netherlands Malaysian Meteorological Service, Malaysia now at: California Institute of Technology, USA Received: 15 November 2002 – Accepted: 16 January 2003 – Published: 10 February 2003 Correspondence to: M. D. K...