The blister beetle Mylabris cichorii L. (Coleoptera: Meloidae) is a traditional medicinal insect recorded in the Chinese Pharmacopoeia. It synthesizes cantharidin, which kills cancer cells efficiently. Only males produce large amounts of cantharidin. Reference genes are required as endogenous controls for the analysis of differential gene expression in M. cichorii. Our study chose 10 genes as c...

cantharidin is one of the most well- known compounds which has ever been fascinating in medicine due to its effects on human and domestic animals. it is produced naturally by beetles of family meloidae and oedemeridae, however a considerable spectra of other insects sequestered it too. cantharidin along with the other analogue, palasonin, which has a methyl group less than it, found in the hemo...

In the order Coleoptera, cantharidin is produced by two families, Meloidae (true blister beetles) and Oedemeridae (false blister beetles). Cantharidin is of veterinary and medical importance, since it is super toxic to animals and humans. The present work was conducted aiming to review the cantharidin investigation and cantharidin toxicosis to animals including pathology, symptomatology, preven...

background: in order to study the biology of mylabris impressa stillata , which little is known about, a laboratory colony was established. methods: in this descriptive study, the laboratory colony was collected from toyserkan county in hamedan province, iran. to feed the larval instars, a parallel colony of the grasshopper, schistocerca gregaria was set-up. meloid females lived for several mon...