Four patients with idiopathic membranous glomerulonephritis, heavy proteinuria and progressive renal failure received azathioprine and prednisolone. Renal function improved in all four and proteinuria declined sharply in three. We suggest that treatment with azathioprine and prednisolone may be of benefit in this form of idiopathic membranous glomerulonephritis.

introduction antineutrophil cytoplasmic antibodies (anca)-associated glomerulonephritis (gn) is characterized by necrotizing and crescentic gn with paucity of immunoglobulin (ig) and complement deposition, which is also known as pauci-immune crescentic gn. membranous nephropathy (mn) is characterized by the formation of subepithelial immune deposit with resultant changes in glomerular basement ...

background: nephrotic syndrome and type 1 diabetes mellitus are two common chronic conditions in children. co-existence of these conditions is an extremely rare finding. case presentation: this report presents a 6-year-old boy who was diagnosed with nephrotic syndrome five years ago and type 1 diabetes mellitus in infancy. renal biopsy showed membranous glomerulonephritis, which is a rare histo...

introduction idiopathic membranous nephropathy (mn) is a common cause of adult nephrotic syndrome. recently, m-type phospholipase a2 receptor (pla2-r) has been discovered as the main podocyte antigen in the pathogenesis of idiopathic mn. materials and methods in this mini review, the author searched english-language medline for the terms “membranous nephropathy”, “rituximab”, and “phospholipase...

Stanley de Almeida Araújo, Luiz Flávio Giordano , Ariel Augusto de Britto Rosa , Paula Alves Santos do Carmo, Kinulpe Honorato-Sampaio a Escola de Medicina da Universidade Federal de Ouro Preto, Ouro Preto, MG, Brazil b Centro Especializado em Anatomia Patológica, Belo Horizonte, MG, Brazil c Hospital Universitário São José, Belo Horizonte, MG, Brazil d Centro de Microscopia da Universidade Fed...

BACKGROUND Sjögren's syndrome is a systemic autoimmune disease in which lymphatic cells destroy the salivary and lacrimal glands. Glomerulonephritis is thought to be a rare occurrence in primary Sjögren's syndrome. Furthermore, concurrent glomerular involvement and lymphoma in patients with Sjögren's syndrome has seldom been reported. CASE PRESENTATION A 52-year-old woman with primary Sjögren...