dendritic cells (dcs) induce pathogen-specific t cell responses. we comprehensively studied the effects of addition of maturation stimulus, fibroblasts (fibroblast conditioned medium), pha activated t cells (t cell conditioned medium), and mixture of fibroblast & pha activated t cells (fcm-tccm) conditioned media on maturation of dcs. monocytes were cultured with gm-csf and il-4 for five da...

objective(s) some investigation has indicated that adipose-derived stem cells possess different surface epitopes and differentiation potential according to the localization of fat pad from which the cells were derived. in the present study proliferation capacity and aging of such cells were explored. materials and methods adherent cells were isolated from the collagenase digests of adipose tiss...

purpose: to report the outcomes of conjunctival-limbal autograft (clau) in patients with unilateral total limbal stem cell deficiency (lscd) emphasizing surgical problems, complications, and their management. methods: in this prospective interventional case series, clau combined with amniotic membrane transplantation as a graft was performed on 26 patients with unilateral total lscd due to chem...

Treatment of injuries to peripheral nerves after a segmental defect is one the most challenging surgicalproblems. Therapies for injury are largely ineffective. Therefore, current study wasconducted investigate effects either acellular human umbilical cord tissue powder on repair 1 cm criticalsize radial nerve guided by bovine urinary bladder matrix conduit alone or seeded with mesenchymalstem c...

mesenchymal stem cells (mscs),as the major stem cells for cell therapy, have been studied from different aspects in pre-clinical and clinical settings for more than a decade. these cells modulate the immune system (humoral and cellular immune responses) in vitro by producing soluble factors (anti-inflammatory molecules) and/or making cell-cell contacts. hence they could be used in regenerative ...