in MCF-7 human cancer cell line using magneic PLGA nanoparticles, dextran coated particles and empty PLGA nanoparticles.. Figure 1: Scanning electron microscopy (SEM) of nanoparticles with TEM inset showing distribution of magnetite cores. A) PLGA nanoparticles; B) PLGA microparticles; C) Cellulose nanoparticles. Particles are uniform in size, spherical and have high amounts of encapsulated mag...

Magnetite nanoparticles are of great importance in nanotechnology and nanomedicine and have found manifold applications. Here, the effect of coating of magnetite nanoparticles with organic stabilizers, such as O-phosphoryl ethanolamine, glycerol phosphate, phospho-l-ascorbic acid, phospho-d,l-serine, glycolic acid, lactic acid, d,l-malic acid, and d,l-mandelic acid was studied. Remarkably, this...

Magnetic nanoparticles made of magnetite have the advantage to be biocompatible and to have a good saturation magnetisation. In this work we show that magnetite nanoparticles change their magnetic and chemical characteristics over time, depending on their storage conditions. To determine the oxidation state of the iron in the core of the nanoparticles Mössbauer spectroscopy was used at 4.2 K. T...

In this work, sub-50 nm pegylated mesoporous silica nanoparticles prepared with hydrothermal treatment are shown to have long-term stability in various media at both room and physiological temperature. Compared to bare mesoporous silica nanoparticles, the highly pegylated mesoporous silica nanoparticles show significantly improved biocompatibility and decreased macrophage uptake, making these n...

Based on chelation effect between iron ions and amino groups of chitosan, in situ mineralization of magnetite nanoparticles in chitosan hydrogel under ambient conditions was proposed. The chelation effect between iron ions and amino groups in CS-Fe complex, which led to that chitosan hydrogel exerted a crucial control on the magnetite mineralization, was proved by X-ray photoelectron spectrum. ...

BACKGROUND Magnetic nanoparticles in a variable magnetic field are able to produce heat. This heat (42-45°C) has more selective effect on fast dividing cancer cells than normal tissues. METHODS In this work magnetite nanoparticles have been prepared via co-precipitation and phase identification was performed by powder x-ray diffraction (XRD). Magnetic parameters of the prepared nanoparticles ...

New chiral magnetite nanoparticles with a polymerizable group produced polymer composite films on an electrode surface and the hybrid nanotubes of magnetite nanoparticles and polythiophene from their template-based electropolymerization.

background nowadays, removal of heavy metals from the environment is an important problem due to their toxicity. objectives in this study, a modified method was used to synthesize chitosan-coated magnetite nanoparticles (ccmn) to be used as a low cost and nontoxic adsorbent. ccmn was then employed to remove hg2+ from water solutions. materials and methods to remove the highest percentage of mer...

Core-shell magnetic nanoparticles have received significant attention recently and are actively investigated owing to their large potential for a variety of applications. Here, the synthesis and characterization of bimetallic nanoparticles containing a magnetic core and a gold shell are discussed. The gold shell facilitates, for example, the conjugation of thiolated biological molecules to the ...

Magnetic nanoparticle-mediated intracellular hyperthermia has been a largely experimental modality of hyperthermia, but this treatment modality has the potential to achieve tumor targeted heating without any side effects. The technique consists of targeting magnetic nanoparticles to tumor tissue and then applying an external alternating magnetic field to induce heat generation by the magnetic n...