نتایج جستجو برای: metastasis of cervical cancer

تعداد نتایج: 21370511  

Journal: : 2022

EVALUATION OF THE EFFECTS IBUPROFEN CYTOTOXIC DOSE ON EXPRESSION LEVEL EXTRACELLULAR MATRIX DEGRADING MMP-9 AND ANTI-METASTASIS NM23 GENES IN CERVICAL CANCER CELLS

F. HOMAIE, N. SHARIFY, Z. YOUSEFI,

 ABSTRACT Carcinoma of the cervix is a common neoplasm and accounts for a considerable number of cervical diseases that lead to death in developing countries. In these countries early detection and improved methods of treatment have resulted in comparatively better control of the cancer and long survival however, invasive and metastatic disease still occurs. The authors present the case report ...

پایان نامه :دانشگاه تربیت معلم - تهران - دانشکده زیست شناسی 1391

بررسی تآثیر کورکومین بر بیان آکواپورین5 در سلول های سرطانی روده بزرگ انسان(ht-29) سرطان روده بزرگ جزو بیماری های خطرناک بوده و از نظر شیوع سومین سرطان شایع و دومین علت مرگ ومیر ناشی از سرطان در جهان محسوب می شود. خطرابتلا به این سرطان تحت تاثیر دو عامل محیطی وفاکتورهای ژنتیکی می باشد. آکواپورین ها، پروتئین های کانال آبی بوده که نقش مهمی را در انتقال آب در بافتهای اندوتلیالی و اپی تلیالی بر عهد...

Behnamfar Z Dehghani A Godarzi A Karimi Zarchi M, Malekzadeh M Mousavi A

Background: Fertility preservation in young patients with cervical cancer is a novel point which considers these days and in Iran we have a new experiment that was successful. Materials and Methods: Evaluation of literature review and our experiences in conservative management in patients with early stage cervical cancer. The key words in this research were conservative management, young women ...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه بیرجند - دانشکده علوم 1391

in this thesis, we consider a mathematical model of cancer with completely unknown parameters. we study the stability of critical points which are biologically admissible. then we consider a control on the system and introduce situations at which solutions are attracted to critical points and so the cancer disease has auto healing. the lyapunov stability method is used for estimating the un...

Journal: :Asian Pacific journal of cancer prevention : APJCP 2014
Adisak Nartthanarung Kamolrat Thanapprapasr Umaporn Udomsubpayakul Duangmani Thanapprapasr

BACKGROUND To determine survival times of cervical cancer patients with bone metastasis related to the effect of age at the time of cervical cancer diagnosis, we performed the retrospectively analytical study. METHODS A total of 68 cervical cancer patients with bone metastasis were treated at a single hospital, during January 1998 to December 2010. Fifty-two medical records were identified an...

Journal: :journal of reproduction and infertility 0

background: cervical cancer is the second most common malignancy in women worldwide. vaginal bleeding and vaginal discharge are the most common symptoms. although ascites has been reported in cases with cervical cancer, it is due to other causes such as ovarian metastasis. case presentation: a 78-year-old diabetic woman who presented with ascites and abdominopelvic mass was misdiagnosed with ov...

Journal: :Genetics and molecular research : GMR 2015
X L Zhou M Wang

Cervical cancer is associated with abnormal expression of multiple genes. Survivin and Bcl-2 proteins are apoptosis inhibitors. The tumor suppressor gene CD82, which encodes the protein KAI1, is downregulated in cervical cancer, and is associated with differentiation degree. We investigated the expression levels of three proteins and their correlation with metastasis in cervical cancer by compa...

2018
Run Tian Xiaofang Li Yan'e Gao Yue Li Pei Yang Kunzheng Wang

Lymph node (LN) metastasis at an early stage of cervical cancer is often an indicator of poor prognosis and is critical for subsequent adjuvant therapy. The current study aimed to identify aberrant gene signatures and biomarkers of metastasis for patients with cervical cancer. RNA-sequencing data of 132 LN negative (N0) and 60 LN positive (N1) cervical cancer samples obtained from The Cancer Ge...

2017
Rong Zhang Huan Lu Yuan-yuan Lyu Xiao-mei Yang Lin-yan Zhu Guang-dong Yang Peng-cheng Jiang Yuan Re Wei-wei Song Jin-hao Wang Can-can Zhang Fei Gu Tian-jiao Luo Zhi-yong Wu Cong-jian Xu

Cervical cancer is an infectious cancer and the most common gynecologic cancer worldwide. E6/E7, the early genes of the high-risk mucosal human papillomavirus type, play key roles in the carcinogenic process of cervical cancer. However, little was known about its roles in modulating tumor microenvironment, particular extracellular matrix (ECM). In this study, we found that E6/E7 could regulate ...

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