Background & Aims: In this study the efficacy of traditional method, methadone tapering method and rapid method as three opiate detoxification treatments was compared based on demographic features and naltrexone consumption in a 6- month follow up. Method: This Cohort prospective study was performed on 140 opioid addict men referred to opiate detoxification center of Shahid Beheshti Hospital, K...

Slow downtitration as a methadone discontinuation method is time-consuming and associated to high dropout rates. Whereas ultra-rapid opiate detoxification methods have recently gained some popularity, they are expensive and may be associated with particular problems in methadone patients. ln the present study, a 3-day detoxification procedure accelerated with a unique dose of naltrexone was use...

This paper describes the use of morphine to reduce severity and duration of withdrawal symptoms while undergoing rapid opiate detoxification (ROD) from methadone under medical supervision. A pilot study of 24 randomly selected patients, some using heroin and others being dosed on methadone were surveyed between two months and three months from the time of their detoxification to gauge subjectiv...

background: the common detoxification method is replacement of long effect opiate by short effect opiate and then reducing its amount gradually. more modern method is ultra rapid opiate detoxification (urod) by opiate antagonists, which is performed by general anesthesia. the advantages of two methods have not been confirmed. this study aimed to compare effectiveness and withdrawal rate in both...

we reports a six-year-old child with autistic disorder and methadone intoxication. developmental disorders may mislead the caretakers and doctors to interpret the clinical manifestation and behavioral changes of these patients. methadone indigestion can be fatal in children even in a tiny amount and cardiac monitoring should be performed at least for the first 24 hours. the pervasive prescripti...

Twenty-six in-patients with Diagnostic and Statistical Manual version IV (DSM-IV) criteria for opioid dependence were selected at random to receive either a combination of an 11-day low-dose buprenorphine and a 14-day carbamazepine regimen (n = 14) or a combination of an 11-day methadone and a 14-day carbamazepine regimen (n = 12) in a double-blind, randomized 14-day in-patient detoxification t...

Background: About 8 percent of Iranian adult population are illicit drug abusers. Affected persons grow more each day. Ominous consequences such as divorce, prostitution, murder and other crimes and infectious diseases such as AIDS and hepatitis take place following drug abuse, as well as a loss equall to 29% of national income for our country. Traditional treatment methods wasted too much ti...

BACKGROUND In the United Kingdom (UK), there is an extensive market for the class 'A' drug heroin and many heroin users spend time in prison. People addicted to heroin often require prescribed medication when attempting to cease their drug use. The most commonly used detoxification agents in UK prisons are currently buprenorphine and methadone, both are recommended by national clinical guidelin...

BACKGROUND In China, the Compulsory Detoxification Centres are the main response for people who use illegal drugs. Due to high relapse rates among people released from the Compulsory Detoxification Centres, it is likely that they may seek medical help, including Methadone Maintenance Treatment (MMT) services, at some point. Therefore, better understanding of the attitudes and beliefs of people ...

detoxification of children who are born from substance dependent mothers or those who are substance dependent themselves as a result of being abused by their families is a major concern. this report describes withdrawal symptoms and the way of abstinence in a 2.5 year-old girl who was dependent to opium. âfter that she was given opium for nearly two years suppress withdrawal symptoms, methadone...