background : methadone is considered as a good choice for maintenance treatment program (mmtp) in opioid addicted individuals. qt interval prolongation was reported previously in methadone chronic usersespecially in high dose prescription. qt-interval prolongation predisposes patients to lethal dysrhythmia. this is a report of corrected qt(qtc) prolongation due to acute methadone poisoning. to ...

Fourteen patients with severe cancer pain participated in a trial of methadone given in a fixed dose (10 mg) but at intervals selected by the patients themselves during the loading phase. The aim was to achieve rapid pain relief while avoiding the risk of toxicity from accumulation of methadone. As expected, the dosage intervals increased gradually over the first few days of treatment, the dail...

In post-mortem investigations of fatal intoxication, it is challenging to determine which drug(s) were responsible for the death, and drugs did not. This study aims provide femoral blood drug levels in lethal intoxication control cases, where cause death was other than intoxication. The reference values could assist interpretation toxicological results routine casework. To this end, all from 20...

Emergency medical services received a telephone call from a mother reporting that her three-month-old daughter “turned blue and then stopped breathing” after a prolonged period of crying. On arrival, paramedics found an infant making minimal respiratory efforts with a heart rate of 100 beats/min. Bag-mask ventilation was initiated on the scene. During transport to hospital, she had no spontaneo...

Introduction : Rhabdomyolysis is characterized by a muscle injury that leads to the release of intracellular contents/constituents into systemic circulation. Aim We examined association between severity clinical presentation and creatinine phosphokinase values in patients with rhabdomyolysis acutely intoxicated psychotropic chemical substances. Materials methods This clinically controlled prosp...

Introduction Phenibut is a synthetic γ-aminobutyric acid (GABA) agonist used to treat symptoms of mental disorders like anxiety and insomnia. The substnce licensed widely in Russia. Its recreational use increasing many countries as it easily accessible online. In recent years, several case reports phenibut intoxication withdrawal have been published worldwide. Objectives We present report with ...

how to cite this article: jabbehdari s, farnaghi f, shariatmadari sf, jafari j, mehregan ff, karimzadeh p. accidental children poisoning with methadone: an iranian pediatric sectional study. iran j child neurol. 2013 autumn;7(7): 32-34. objective toxic poisoning with methadone is common in children in iran. our study was carried out due to the changing pattern of methadone poisoning in recent y...

Scientific interest in poisoning by synthetic opioids, particular Methadone, is due to a significant increase their number Kyiv over the past 15 years and fatal consequences. The Aim of Research. Is identify causes associated with methadone determine measures prevent them. Materials Methods. A retrospective analysis medical data 1340 patients Methadone who were treated at Toxicology Center peri...