OBJECTIVE This study aimed to assess the cost impact of administering erythropoiesis-stimulating agents once every 4 weeks instead of one to three times a week to treat anaemia in patients undergoing dialysis. METHODS This was a monocentric retrospective study involving 27 patients who underwent haemodialysis between 2009 and 2013 in a university hospital in Angers, France. The study was a co...

Polyethylene glycol is a synthetic, biodegradable, and water-soluble polyether. Owing to its good biological and material properties, polyethylene glycol shows promise in spinal cord tissue engineering applications. Although studies have examined repairing spinal cord injury with polyethylene glycol, these compelling findings have not been recently reviewed or evaluated as a whole. Thus, we her...

methoxy polyethylene glycol modified magnetite nanoparticles (pegmns) were synthesized and were characterized by scanning electron microscopy (sem), vibrating sample magnetometer (vsm), and x-ray diffraction (xrd) . the adsorption of diazinon onto (pegmns) was investigated by uv spectrophotometry at 236 nm, through batch experiments. the effects of adsorbent dosage, solution ph, contact time, s...

Zinc phthalocyanine labelled polyethylene glycol was prepared to track and monitor the in vivo fate of polyethylene glycol. The chemical structures were characterized by nuclear magnetic resonance and infrared spectroscopy. Their light stability and fluorescence quantum yield were evaluated by UV-Visible and fluorescence spectroscopy methods. The interaction of zinc phthalocyanine labelled poly...

This study presents detection of free polyethylene glycol (PEG) and conjugated PEG in western blot assay using anti-PEG rabbit monoclonals specific to methoxy group of PEG. In a chromogenic western blot assay, detection limit (DL) for free and PEGylated protein was 2.5 μg and 0.5 μg, respectively. Using chemiluminescence substrate, DL of PEGylated granulocyte colony stimulating factor (GCSF) wa...

Background: Pegylated Interferon Alpha-2b is synthesized via the use of PEG (polyethylene glycol). It formulated attaching a 12kDa mono methoxy polyethylene glycol moiety to recombinant human protein. acts binding (JAK/STAT) Janus kinase signal transducer and activator transcription interferon receptor. The /Virafin binds (IFNAR1/2) alpha receptor 1 2. better known as Virafin has been approved ...

The safety of polyethylene glycol plus ascorbic acid has not been fully investigated in patients with renal insufficiency. High-dose ascorbic acid could induce hyperoxaluria, thereby causing tubule-interstitial nephritis and renal failure. This study aims to evaluate the safety and efficacy of polyethylene glycol plus ascorbic acid in patients with chronic kidney disease.We retrospectively revi...