Computed tomographic (CT) and surgical findings were correlated retrospectively in 51 patients with preoperative diagnoses of prolactin-secreting pituitary microadenomas. Thirty-nine had microadenomas at surgery. Twenty-three had identifiable discrete lesions. Of these, 21 had microadenomas and two did not; these two groups could not be distinguished reliably. Six patients with proven microaden...

OBJECTIVE Hyperprolactinemia may be due to various etiological factors and may present with different signs and symptoms. It is relatively less frequent in childhood than in adulthood. The aim of this study was to evaluate retrospectively the clinical course and outcome of hyperprolactinemia in pediatric patients. METHODS We investigated the records of 21 patients with hyperprolactinemia who ...

background & importance: the aim of this study was to demonstrate the result of transsphenoid microsurgery for cushing disease in our center and comparing the results in details with other articles, to achieve the best decision for patients management in future. case presentation: between 1991 to 2015, 50 patients suffering from cushing disease were operated. before operation, endocrine tests a...

Thirty-seven patients with suspected pituitary tumors were evaluated prospectively with MR imaging at 1.5 T. MR detected a microadenoma at its correct location in all eight patients who underwent transsphenoidal surgery, while CT showed a focal abnormality in the correct location in only four of the eight patients. In patients who were clinically and endocrinologically considered to harbor a mi...

Human colorectal microadenomas are considered the earliest detectable premalignant lesions in the colon. They can be identified as aggregates of enlarged crypts with thicker epithelial linings and elongated luminal openings on the colonic mucosal surface after methylene blue staining and observation under a dissecting microscope. Multiple lines of evidence suggest that a central role in neoplas...

UNLABELLED The aim of the study was to investigate symptoms of hyperprolactinemia such as oligomenorrhea, amenorrhea, galactorrhea, and correlation between hyperprolactinemia and MRI of hypophysis in infertile women. MATERIAL AND METHODS During the 10 years period, we have studied 87 patients investigated for infertility causes and with hyperprolactinemia findings, in our patients we have con...